{"id":"W2637203036","doi":"10.1002/slct.201700347","title":"Click Glycosylation for the Synthesis of 1,2,3‐Triazole‐Linked Picropodophyllotoxin Glycoconjugates and Their Anticancer Activity","year":2017,"lang":"en","type":"article","venue":"ChemistrySelect","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lakehead University","funders":"Chinese Academy of Sciences","keywords":"Glycoconjugate; Podophyllotoxin; Chemistry; Click chemistry; Glycosylation; Moiety; Triazole; Stereochemistry; Cycloaddition; Residue (chemistry); 1,2,3-Triazole; Biochemistry; Combinatorial chemistry; Catalysis; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001894305,0.0002454562,0.0003227937,0.000009097645,0.0007482031,0.0001155242,0.0005911679,0.0001838256,0.0001668604],"category_scores_gemma":[0.0009535505,0.0001831563,0.0001616039,0.00005154379,0.0004303425,0.00009549775,0.0001148399,0.0001950191,0.000001773735],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004243151,"about_ca_system_score_gemma":0.00007382163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006265879,"about_ca_topic_score_gemma":0.000009212241,"domain_scores_codex":[0.9989321,0.000006083193,0.0002685199,0.0004019994,0.0001150406,0.0002763135],"domain_scores_gemma":[0.9971089,0.001169241,0.0004520115,0.001063757,0.0001261159,0.00008001827],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000141522,0.00007155666,0.00137063,0.0003451292,0.00009450573,1.873274e-7,0.00004532818,0.000002390935,0.9809629,0.00005011154,0.0001921426,0.01672355],"study_design_scores_gemma":[0.000518039,0.000007285624,0.001543152,0.00006776514,0.00008325549,0.000006951803,0.00006061711,0.001170695,0.9915743,0.0004159946,0.004345589,0.000206396],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928669,0.0002335974,0.0003357349,0.001038592,0.00002221374,0.0002050186,0.0002073934,0.00005073748,0.00503985],"genre_scores_gemma":[0.9983037,0.0001919446,0.00009060915,0.00001346003,0.0003186135,0.0003473755,0.00001897227,0.00002869463,0.0006866536],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01651715,"threshold_uncertainty_score":0.7468898,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02433294529849641,"score_gpt":0.2847630798025386,"score_spread":0.2604301345040422,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}