{"id":"W2637203036","doi":"10.1002/slct.201700347","title":"Click Glycosylation for the Synthesis of 1,2,3‐Triazole‐Linked Picropodophyllotoxin Glycoconjugates and Their Anticancer Activity","year":2017,"lang":"en","type":"article","venue":"ChemistrySelect","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lakehead University","funders":"Chinese Academy of Sciences","keywords":"Glycoconjugate; Podophyllotoxin; Chemistry; Click chemistry; Glycosylation; Moiety; Triazole; Stereochemistry; Cycloaddition; Residue (chemistry); 1,2,3-Triazole; Biochemistry; Combinatorial chemistry; Catalysis; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001126213,0.0003045953,0.0001893771,0.0001238645,0.00006768622,0.0001762579,0.0001304838,0.0002143516,0.0004980716],"category_scores_gemma":[0.0001170822,0.0001057056,0.000224642,0.0001984134,0.0001062516,0.000185327,0.0001911654,0.0002963722,0.0001563749],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002152575,"about_ca_system_score_gemma":0.0001230879,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002645857,"about_ca_topic_score_gemma":0.0003865646,"domain_scores_codex":[0.9999329,0.00001295742,0.00000588788,0.00001037117,0.00001680234,0.00002117141],"domain_scores_gemma":[0.9999509,0.000005717869,0.00001749663,0.00000758239,0.000006850694,0.00001151739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003492361,0.00002019458,0.0001080481,0.00002869228,0.000005187482,0.0001164118,0.00001486031,0.000257662,0.9970925,0.0001509898,0.0000477975,0.002122734],"study_design_scores_gemma":[0.000009969597,0.0002481714,0.001420197,0.000002877982,0.00001321856,0.0002332153,0.000007982899,0.0009276479,0.9956359,0.00003461801,0.001460803,0.000005423551],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9825386,0.000822212,0.01447978,0.00007543369,0.00002714411,0.00007038324,0.0002483591,0.00009978722,0.001638227],"genre_scores_gemma":[0.9924831,0.0006657203,0.00528277,0.00003493671,0.000005182692,0.00003020362,0.0002506196,0.00001089076,0.001236649],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004980716,"threshold_uncertainty_score":0.001666248,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02433294529849641,"score_gpt":0.2847630798025386,"score_spread":0.2604301345040422,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}