{"id":"W2643935873","doi":"10.1200/jco.2017.35.15_suppl.2502","title":"Ceritinib plus nivolumab (NIVO) in patients (pts) with anaplastic lymphoma kinase positive (ALK+) advanced non-small cell lung cancer (NSCLC).","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Internal medicine; Ceritinib; Anaplastic lymphoma kinase; Maculopapular rash; Gastroenterology; Rash; Nivolumab; Lung cancer; Oncology; Cancer; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006254969,0.0005572471,0.0009258148,0.0001860202,0.0002668234,0.0004539053,0.0002816635,0.0005070877,0.001191947],"category_scores_gemma":[0.0004712273,0.000272507,0.0006129199,0.0002355419,0.0002476354,0.0004635701,0.0002204209,0.0009104082,0.0003846832],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006563262,"about_ca_system_score_gemma":0.0007496489,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006735569,"about_ca_topic_score_gemma":0.00244932,"domain_scores_codex":[0.9998135,0.00006896959,0.00001459414,0.00004569375,0.00001932342,0.0000380652],"domain_scores_gemma":[0.9997941,0.000033743,0.00004758012,0.000009724398,0.00001094405,0.0001040088],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5642591,0.02729828,0.08847328,0.001103191,0.001256629,0.0009992378,0.0005187553,0.007031682,0.05070557,0.0002220517,0.003618796,0.2545133],"study_design_scores_gemma":[0.1080891,0.7239158,0.1426781,0.00008432639,0.001005699,0.001847904,0.0001580372,0.004690162,0.009606224,0.0002481759,0.007633131,0.00004339625],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979299,0.001000204,0.00008092371,0.0001027805,0.00002788467,0.0002141481,0.000129467,0.00001447279,0.0005002304],"genre_scores_gemma":[0.9985862,0.0003875259,0.00023201,0.00008861835,0.00003324101,0.0001149648,0.0001813407,0.000002442597,0.0003737806],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001191947,"threshold_uncertainty_score":0.004761994,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02739214081189677,"score_gpt":0.4242340125112666,"score_spread":0.3968418716993699,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}