{"id":"W2649439238","doi":"10.1089/adt.2017.787","title":"A High-Throughput Screening Assay for NKCC1 Cotransporter Using Nonradioactive Rubidium Flux Technology","year":2017,"lang":"en","type":"article","venue":"Assay and Drug Development Technologies","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Aurora College","funders":"","keywords":"High-throughput screening; Throughput; HEK 293 cells; Computational biology; Assay sensitivity; Rubidium; Chemistry; Biology; Computer science; Biochemistry; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001268931,0.0009689203,0.001176874,0.00101588,0.0004879529,0.0005989715,0.0008438078,0.0008868661,0.00147895],"category_scores_gemma":[0.0008142033,0.0004667315,0.0006375621,0.0006501764,0.0003836274,0.0004495605,0.0006166917,0.0009610577,0.001192687],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004678939,"about_ca_system_score_gemma":0.0005218611,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000541303,"about_ca_topic_score_gemma":0.001287707,"domain_scores_codex":[0.9980849,0.0004634556,0.0001459196,0.0003151196,0.0008749892,0.0001156298],"domain_scores_gemma":[0.9994375,0.0001895382,0.00007933708,0.00007693017,0.0001678985,0.00004881573],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005105758,0.00005454398,0.0002272235,0.000110917,0.00001352321,0.0000515966,0.00002201971,0.0001689643,0.9946446,0.00009655808,0.0002536152,0.004305359],"study_design_scores_gemma":[0.00001685439,0.0003416886,0.001534212,0.000007261216,0.00002688591,0.0003248882,0.0000130969,0.002224941,0.9923066,0.00005813559,0.003121496,0.00002404622],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.3766607,0.005497328,0.5975865,0.0005522792,0.0003227862,0.00193371,0.003874308,0.00512081,0.008451489],"genre_scores_gemma":[0.5817516,0.004597599,0.3847408,0.0003901446,0.0001238276,0.002918242,0.007220701,0.0003018532,0.01795519],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.00147895,"threshold_uncertainty_score":0.006710887,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02226887992356323,"score_gpt":0.2637471240845943,"score_spread":0.241478244161031,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}