{"id":"W26500243","doi":"10.1007/0-306-46881-6_300","title":"Modulation of specificity in cyclic antimicrobial peptides by amphipathicity","year":2006,"lang":"en","type":"book-chapter","venue":"Kluwer Academic Publishers eBooks","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; University of Alberta","funders":"","keywords":"Cyclic peptide; Antimicrobial; Peptide; Chemistry; Antimicrobial peptides; Amphiphile; Gramicidin S; Biochemistry; Gramicidin; Membrane; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001571441,0.0003087346,0.000264089,0.0001806086,0.0001733901,0.0004656927,0.0002991408,0.0003820214,0.002009314],"category_scores_gemma":[0.000158372,0.0001646492,0.0001647354,0.0002090511,0.0002873087,0.0005437876,0.0003724353,0.001107462,0.0008220401],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002389576,"about_ca_system_score_gemma":0.0001360127,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009567868,"about_ca_topic_score_gemma":0.0001517146,"domain_scores_codex":[0.9999309,0.000008486944,0.000003755457,0.00001103146,0.00003253211,0.00001327887],"domain_scores_gemma":[0.9999453,0.00002625654,0.000007446238,0.000004273882,0.000009160593,0.00000759765],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007583167,0.00004845125,0.00005771996,0.0003000528,0.000004591002,0.0001974733,0.00009832269,0.0005151341,0.8947682,0.01608347,0.002458562,0.08539213],"study_design_scores_gemma":[0.00003439335,0.0005479025,0.001118593,0.0001384212,0.0000177007,0.00183628,0.00005106943,0.001863241,0.7358602,0.008881777,0.2496143,0.00003615526],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4514303,0.2012237,0.05591327,0.002747488,0.002242515,0.0002260072,0.0003464175,0.0008463744,0.2850239],"genre_scores_gemma":[0.6747453,0.08965165,0.03764751,0.003087027,0.0006456008,0.0003071908,0.0004730268,0.0002454591,0.1931973],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002009314,"threshold_uncertainty_score":0.006721795,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01571767220259055,"score_gpt":0.220254378616514,"score_spread":0.2045367064139235,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}