{"id":"W2652154361","doi":"10.1016/j.chembiol.2017.05.026","title":"Sam68 Allows Selective Targeting of Human Cancer Stem Cells","year":2017,"lang":"en","type":"article","venue":"Cell chemical biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University; McMaster University","funders":"Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Wnt signaling pathway; Cancer stem cell; Regulator; Stem cell; Cell biology; Cancer research; Signal transduction; Biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001333147,0.0001303132,0.0001890788,0.0000166245,0.0001239751,0.00001133927,0.0003139122,0.0002766215,0.0000264964],"category_scores_gemma":[0.00002957421,0.0001194777,0.00008827229,0.00001960369,0.0002409911,0.000002023257,0.0001794163,0.00009879059,0.000004320842],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001485583,"about_ca_system_score_gemma":0.00003662719,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001014676,"about_ca_topic_score_gemma":0.00001490657,"domain_scores_codex":[0.999126,0.0000416266,0.0002221427,0.0003364679,0.00004759903,0.0002261367],"domain_scores_gemma":[0.9992034,0.00001467656,0.0002505665,0.0003592253,0.0001088334,0.00006323592],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002000752,0.00003738521,0.01029204,0.00001798333,0.00002288911,2.88375e-7,0.00002396106,0.000005135698,0.9880114,0.00004838078,0.000283498,0.001237047],"study_design_scores_gemma":[0.0003100582,0.0001312014,0.000449169,0.000004979235,0.00001440448,1.20572e-7,0.00001198004,0.00001367023,0.9933497,0.0003244888,0.005249059,0.0001411671],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938367,0.001689286,0.0001598204,0.00004305971,0.0001592553,0.0001022831,0.00002634326,0.000005697957,0.003977554],"genre_scores_gemma":[0.9986511,0.0002989459,0.0003294958,0.0000340455,0.000264306,0.00001516029,0.0000617921,0.00001576478,0.0003293951],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009842869,"threshold_uncertainty_score":0.487216,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0164878330207926,"score_gpt":0.2899439975872841,"score_spread":0.2734561645664915,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}