{"id":"W2659875471","doi":"10.1016/j.clgc.2017.06.004","title":"Real-world Characteristics and Outcomes of Patients With Metastatic Castration-resistant Prostate Cancer Receiving Chemotherapy Versus Androgen Receptor-targeted Therapy After Failure of First-line Androgen Receptor-targeted Therapy in the Community Setting","year":2017,"lang":"en","type":"article","venue":"Clinical Genitourinary Cancer","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":false,"ca_institutions":"Group for Research in Decision Analysis","funders":"Astellas Pharma; Sanofi","keywords":"Medicine; Prostate cancer; Internal medicine; Androgen receptor; Docetaxel; Hazard ratio; Androgen deprivation therapy; Prostate-specific antigen; Oncology; Taxane; Enzalutamide; Cancer; Breast cancer; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001105408,0.0004045645,0.001022881,0.0001371329,0.0004121939,0.00006177773,0.0003890349,0.0001341976,0.0002692296],"category_scores_gemma":[0.0001811548,0.0002422335,0.0001825436,0.0002723327,0.0006341599,0.0002202756,0.0000889631,0.0007304513,0.000001041783],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001597031,"about_ca_system_score_gemma":0.0003987263,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001796805,"about_ca_topic_score_gemma":0.002421311,"domain_scores_codex":[0.9969233,0.0005829519,0.001038152,0.0004337493,0.0005614144,0.0004604201],"domain_scores_gemma":[0.9966871,0.0007981732,0.0008999995,0.0009363334,0.0005077441,0.0001706656],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02535026,0.001136153,0.9405163,0.0002038188,0.0009800553,0.00002364542,0.00212253,0.000003606523,0.0008941013,6.827784e-7,0.0001874286,0.02858144],"study_design_scores_gemma":[0.01868363,0.003051727,0.9723783,0.0004084285,0.0001210881,6.959377e-7,0.0004276246,0.0000210373,0.003325203,0.00001281226,0.001312516,0.0002569139],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992093,0.002076256,6.358897e-7,0.002716992,0.0002514486,0.001986238,0.0008095447,0.00002081957,0.00004511341],"genre_scores_gemma":[0.9707943,0.02741355,0.0005452679,0.0001778345,0.0001592843,0.0004343757,0.0002562691,0.00006321005,0.0001559086],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03186204,"threshold_uncertainty_score":0.9877995,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06233659836217686,"score_gpt":0.3819573128623433,"score_spread":0.3196207145001664,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}