{"id":"W2659875471","doi":"10.1016/j.clgc.2017.06.004","title":"Real-world Characteristics and Outcomes of Patients With Metastatic Castration-resistant Prostate Cancer Receiving Chemotherapy Versus Androgen Receptor-targeted Therapy After Failure of First-line Androgen Receptor-targeted Therapy in the Community Setting","year":2017,"lang":"en","type":"article","venue":"Clinical Genitourinary Cancer","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":false,"ca_institutions":"Group for Research in Decision Analysis","funders":"Astellas Pharma; Sanofi","keywords":"Medicine; Prostate cancer; Internal medicine; Androgen receptor; Docetaxel; Hazard ratio; Androgen deprivation therapy; Prostate-specific antigen; Oncology; Taxane; Enzalutamide; Cancer; Breast cancer; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007145651,0.0002551742,0.0004836545,0.0005510537,0.000578814,0.00115681,0.0005961265,0.0008915837,0.002410834],"category_scores_gemma":[0.005478836,0.0002276935,0.0008618113,0.001203518,0.0005842269,0.001241757,0.000914327,0.001129661,0.000219354],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001144949,"about_ca_system_score_gemma":0.0006632085,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01239811,"about_ca_topic_score_gemma":0.01609046,"domain_scores_codex":[0.999002,0.0003265978,0.00009781661,0.0002113671,0.000085771,0.0002764505],"domain_scores_gemma":[0.9958978,0.0006715172,0.001858933,0.0001231363,0.0002198742,0.00122873],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00106446,0.0001693552,0.9967183,0.00001800983,0.0001496709,0.00009039901,0.0001051888,0.0001798521,0.00005997148,0.00003951614,0.0002593197,0.001146045],"study_design_scores_gemma":[0.00006890974,0.0007619613,0.9968182,0.00001282737,0.00007503825,0.0002668707,0.001050782,0.0005727316,0.00003170182,0.0001059884,0.0002124074,0.00002262811],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988765,0.0001845007,0.00002991381,0.0001037659,0.000007969734,0.000008956854,0.0005496946,0.000001983803,0.0002365622],"genre_scores_gemma":[0.9993147,0.00005323998,0.00001613038,0.00003458522,0.00001013733,0.00000503061,0.0005282654,0.00000137141,0.00003651575],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01239811,"threshold_uncertainty_score":0.02465194,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06233659836217686,"score_gpt":0.3819573128623433,"score_spread":0.3196207145001664,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}