{"id":"W2661218045","doi":"10.1002/iid3.151","title":"In vivo targeting of protein antigens to dendritic cells using anti‐DEC‐205 single chain antibody improves HIV Gag specific CD4<sup>+</sup> T cell responses protecting from airway challenge with recombinant vaccinia‐gag virus","year":2017,"lang":"en","type":"article","venue":"Immunity Inflammation and Disease","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"European and Developing Countries Clinical Trials Partnership; National Research Foundation of Korea; Third World Academy of Sciences; Grand Challenges Canada; Ministry of Science, ICT and Future Planning; National Research Foundation","keywords":"Antigen; Ovalbumin; In vivo; Dendritic cell; Biology; Antibody; Virology; T cell; Recombinant DNA; Immunology; Molecular biology; Immune system; Cell biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.001012462,0.0004386537,0.0006210129,0.0004267179,0.001387952,0.0001787059,0.0004833236,0.0002385121,0.0003033125],"category_scores_gemma":[0.0007168407,0.0004067825,0.0001213399,0.0001684456,0.0003000342,0.0007051422,0.0002454374,0.0005138057,0.00003525239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008035015,"about_ca_system_score_gemma":0.000226567,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001095354,"about_ca_topic_score_gemma":0.00004062281,"domain_scores_codex":[0.9966151,0.001363991,0.0008257467,0.0004887444,0.0001150913,0.0005913345],"domain_scores_gemma":[0.9976993,0.0003695417,0.0006663455,0.0009746596,0.0001811786,0.0001089769],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006878935,0.0005315234,0.001035893,0.0001809127,0.00007679378,0.00004250729,0.004842777,0.00008611046,0.9844322,0.00002736639,0.00002833061,0.001836663],"study_design_scores_gemma":[0.003540098,0.0005522658,0.007591866,0.0008101092,0.0000464229,0.000007553253,0.003176778,0.0002592285,0.9808252,0.00007473914,0.002572615,0.0005431511],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993297,0.003861071,0.0002454415,0.0004842358,0.0002077277,0.001612693,0.0001428398,0.00006180306,0.00008713656],"genre_scores_gemma":[0.9982774,0.0004470571,0.0004427929,0.00003371323,0.00004893556,0.00006006927,0.00006608137,0.00005473289,0.0005692337],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006555974,"threshold_uncertainty_score":0.9999121,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01804686471043003,"score_gpt":0.2551580547054816,"score_spread":0.2371111899950515,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}