{"id":"W2667918582","doi":"10.1371/journal.pone.0179327","title":"Increasing procaspase 8 expression using repurposed drugs to induce HIV infected cell death in ex vivo patient cells","year":2017,"lang":"en","type":"article","venue":"PLoS ONE","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"National Center for Advancing Translational Sciences; National Institute of Allergy and Infectious Diseases; National Institutes of Health; Georgia Clinical and Translational Science Alliance; Minneapolis Medical Research Foundation; University of Minnesota","keywords":"Ex vivo; Cytotoxic T cell; Programmed cell death; Apoptosis; In vivo; Context (archaeology); Biology; Medicine; Virology; Immunology; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001805547,0.0003217529,0.0004135518,0.0002033541,0.0001239321,0.0003741582,0.0001747018,0.0002303404,0.003337897],"category_scores_gemma":[0.0001089433,0.0001295598,0.0003423106,0.000177193,0.0001541839,0.0002386325,0.0001578594,0.0009618634,0.0005824346],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001511966,"about_ca_system_score_gemma":0.0001485643,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000184316,"about_ca_topic_score_gemma":0.0003429083,"domain_scores_codex":[0.9998368,0.00003362801,0.00001951109,0.00003662533,0.00003760195,0.00003577199],"domain_scores_gemma":[0.9999419,0.00001773729,0.00001276764,0.000009623029,0.000007219843,0.00001063926],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006726668,0.0004873184,0.0003607078,0.0001057598,0.00002186628,0.00008934286,0.00003431369,0.0002004659,0.9920546,0.00008906968,0.0001922401,0.005691695],"study_design_scores_gemma":[0.0001234145,0.005858212,0.00262889,0.000006527639,0.00004135873,0.0003651488,0.00003442202,0.0006244401,0.9879665,0.00003806701,0.002307856,0.000005235361],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994849,0.001452597,0.001655147,0.00009750578,0.00006798813,0.00008970481,0.0004833412,0.00005524977,0.001249423],"genre_scores_gemma":[0.9921563,0.00138741,0.002693387,0.00008947361,0.00002264621,0.0001374893,0.0009824322,0.00001195168,0.002519031],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003337897,"threshold_uncertainty_score":0.01116633,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04480178734441223,"score_gpt":0.2628999957706636,"score_spread":0.2180982084262514,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}