{"id":"W266794678","doi":"10.1182/blood.v122.21.514.514","title":"Whole Genome Sequencing Of Chronic Myeloid Leukemia (CML)-Derived Induced Pluripotent Stem Cells (iPSC) Reveals Faithful Genocopying Of Highly Mutated Primary Leukemic Cells","year":2013,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Induced pluripotent stem cell; Biology; Cancer research; Myeloid leukemia; KLF4; SOX2; Stem cell; Myeloid; Progenitor cell; Genetics; Gene; Embryonic stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001306411,0.0001847,0.0001529886,0.0002245116,0.0001035697,0.0001865419,0.0001140798,0.0002199876,0.0009849684],"category_scores_gemma":[0.0001353361,0.00009912115,0.000214052,0.000202907,0.0001489499,0.00005673127,0.0001751599,0.000332274,0.0003585238],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001009329,"about_ca_system_score_gemma":0.0001028519,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002692116,"about_ca_topic_score_gemma":0.0004984434,"domain_scores_codex":[0.9999257,0.000006743028,0.000008148473,0.00002382718,0.00002564404,0.00000998926],"domain_scores_gemma":[0.9999131,0.00002339925,0.00002179665,0.0000164931,0.00001413619,0.00001102772],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000144144,0.000003322501,0.000214635,0.00001353699,0.000002460507,0.00006676349,0.00001496239,0.00009728214,0.9979394,0.00008300408,0.00004008811,0.001510033],"study_design_scores_gemma":[0.00001045593,0.0001155308,0.01561483,0.000008784562,0.00003516473,0.0006476879,0.00003810305,0.002026014,0.9746395,0.0002070848,0.006651555,0.000005238922],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9463682,0.0004533941,0.04354711,0.0001008584,0.00003668105,0.0001361907,0.006872893,0.0003296326,0.002155048],"genre_scores_gemma":[0.9484869,0.0008856362,0.03688949,0.0001514091,0.00001171291,0.0001224382,0.00964382,0.0001557486,0.003652819],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009849684,"threshold_uncertainty_score":0.003295064,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01788640998757009,"score_gpt":0.2193060988833037,"score_spread":0.2014196888957336,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}