{"id":"W2673967352","doi":"10.1016/j.expneurol.2017.06.022","title":"Sociability impairments in Genetic Absence Epilepsy Rats from Strasbourg: Reversal by the T-type calcium channel antagonist Z944","year":2017,"lang":"en","type":"article","venue":"Experimental Neurology","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":30,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; University of Saskatchewan","funders":"Epilepsy Society; Canadian Institutes of Health Research; Saskatchewan Health Research Foundation; Fondation Brain Canada; Citizens United for Research in Epilepsy; Michael Smith Health Research BC; Genome British Columbia; University of Saskatchewan","keywords":"Calcium channel; Antagonist; Epilepsy; Calcium channel blocker; Psychology; Ictal; L-type calcium channel; T-type calcium channel; Voltage-dependent calcium channel; Childhood absence epilepsy; Internal medicine; Missense mutation; Neuroscience; Endocrinology; Calcium; Medicine; Mutation; Biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.0002961436,0.0003063352,0.0003169092,0.00007025857,0.001322037,0.0001934108,0.001990996,0.0001479945,0.000224587],"category_scores_gemma":[0.0004054338,0.0002532452,0.00008990271,0.0001884375,0.002285977,0.0003402835,0.0008349356,0.0008159349,0.0001709601],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005810559,"about_ca_system_score_gemma":0.0001026975,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006288298,"about_ca_topic_score_gemma":0.00002316462,"domain_scores_codex":[0.9959429,0.0009388073,0.0003683527,0.00127116,0.0004644747,0.001014305],"domain_scores_gemma":[0.9981493,0.0004434237,0.0002140101,0.000952862,0.00002154359,0.0002189085],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004211692,0.0004359923,0.03366575,0.000002143699,0.000002342836,0.0009774592,0.0002469745,0.000007200659,0.9620358,0.00001531103,0.002076376,0.0001134204],"study_design_scores_gemma":[0.0009455788,0.0007572236,0.105233,0.000002010841,0.000002757563,0.0001220612,0.00004999012,0.000359492,0.8912917,0.000160826,0.0008675923,0.0002077502],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930993,0.0001118961,0.000002407994,0.003113147,0.002486704,0.0007313984,0.00006975033,0.0000502286,0.000335209],"genre_scores_gemma":[0.9922009,0.00009591792,0.0000037247,0.007073079,0.0001610069,0.0001103016,0.000001910284,0.00003324667,0.0003198989],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07156724,"threshold_uncertainty_score":0.999992,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06023271286303257,"score_gpt":0.3771944226826422,"score_spread":0.3169617098196096,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}