{"id":"W2683046555","doi":"10.1128/aac.00093-17","title":"<i>In Vitro</i> Activity of the Siderophore Cephalosporin, Cefiderocol, against a Recent Collection of Clinically Relevant Gram-Negative Bacilli from North America and Europe, Including Carbapenem-Nonsusceptible Isolates (SIDERO-WT-2014 Study)","year":2017,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":196,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Shionogi","keywords":"Acinetobacter baumannii; Cephalosporin; Broth microdilution; Stenotrophomonas maltophilia; Microbiology; Meropenem; Bacilli; Enterobacteriaceae; Acinetobacter; Pseudomonas aeruginosa; Biology; Carbapenem; Stenotrophomonas; Minimum inhibitory concentration; Antibiotics; Pseudomonas; Bacteria; Antibiotic resistance; Escherichia coli","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000778639,0.0005404606,0.0004293232,0.0002827351,0.0001545809,0.0003919514,0.0003103879,0.0003347442,0.001395515],"category_scores_gemma":[0.0005757728,0.0002220691,0.0007762042,0.0003588406,0.0001985941,0.0002111762,0.0002020296,0.0004482583,0.0004922201],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000345324,"about_ca_system_score_gemma":0.0004054483,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003005856,"about_ca_topic_score_gemma":0.00337478,"domain_scores_codex":[0.9990404,0.0003286033,0.0001558008,0.000198692,0.0001662177,0.0001102154],"domain_scores_gemma":[0.9993735,0.0001301503,0.0001416626,0.00008483164,0.0002129353,0.00005701006],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00854584,0.002354152,0.0199163,0.0005777744,0.0002215594,0.0002247107,0.0001145514,0.001348462,0.9494873,0.0001053261,0.002680001,0.01442412],"study_design_scores_gemma":[0.0005984789,0.05260283,0.07401939,0.0000534728,0.0003146936,0.0008842534,0.00008438284,0.001294766,0.8635355,0.00004005722,0.006536693,0.00003546366],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898583,0.002265932,0.0007635347,0.0001252385,0.00009183977,0.0002028773,0.004002708,0.00004464679,0.002644848],"genre_scores_gemma":[0.9841584,0.001512675,0.00198393,0.0001957523,0.00009488153,0.0001304523,0.01020055,0.00001819409,0.001705087],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003005856,"threshold_uncertainty_score":0.005976737,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01576817609352346,"score_gpt":0.272573280932022,"score_spread":0.2568051048384985,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}