{"id":"W2683646381","doi":"10.1182/blood.v128.22.708.708","title":"Tet2 Deficiency Leads to an Increased Inflammatory Phenotype in Murine Macrophages","year":2016,"lang":"en","type":"article","venue":"Blood","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Phenotype; Biology; Immune system; Knockout mouse; Immunology; Demethylating agent; Gene expression; Cancer research; Gene; Molecular biology; DNA methylation; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001353373,0.000486365,0.0002781322,0.0003935779,0.000150878,0.0002918547,0.0001601362,0.0003761198,0.002120417],"category_scores_gemma":[0.0000789499,0.0001972981,0.0002915896,0.0001986511,0.0002453526,0.0001298401,0.0002851265,0.0006869995,0.0007156091],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002124253,"about_ca_system_score_gemma":0.0001456001,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003060268,"about_ca_topic_score_gemma":0.0006142661,"domain_scores_codex":[0.9997625,0.00003234366,0.00002809281,0.00005175467,0.00006290262,0.00006241501],"domain_scores_gemma":[0.999781,0.00002664459,0.00005961691,0.00003067323,0.00002063461,0.00008148572],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001110037,0.00001445741,0.000114845,0.00001991306,0.000002417961,0.00005972382,0.000009688056,0.00001877717,0.9993165,0.00002109664,0.00002324571,0.0002883876],"study_design_scores_gemma":[0.00002656637,0.0004307517,0.005285875,0.00001056999,0.00001794207,0.0003705103,0.00004639134,0.0002806823,0.9919168,0.00004711687,0.001561586,0.000005052509],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936789,0.001127432,0.002291124,0.0001220191,0.00004993453,0.00003738818,0.001350214,0.0001601365,0.001182842],"genre_scores_gemma":[0.9894778,0.0008009837,0.002095148,0.0001346096,0.00003009878,0.00009844599,0.001462153,0.00006825433,0.005832548],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002120417,"threshold_uncertainty_score":0.007093489,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007051811318661227,"score_gpt":0.240265832019404,"score_spread":0.2332140207007428,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}