{"id":"W2689512303","doi":"10.1007/s12640-017-9764-3","title":"Assessing Environmental Exposure to β-N-Methylamino-l-Alanine (BMAA) in Complex Sample Matrices: a Comparison of the Three Most Popular LC-MS/MS Methods","year":2017,"lang":"en","type":"article","venue":"Neurotoxicity Research","topic":"Amino Acid Enzymes and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia, Okanagan Campus; University of British Columbia","funders":"","keywords":"Cyanobacteria; Hydrophilic interaction chromatography; Chromatography; Chemistry; Cyanotoxin; Sample preparation; Matrix (chemical analysis); Mass spectrometry; Derivatization; High-performance liquid chromatography; Biology; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001594106,0.0002191086,0.000401965,0.0001208124,0.0005394107,0.0001737484,0.001374252,0.0001954104,0.0000636729],"category_scores_gemma":[0.001178618,0.0001751285,0.0001290325,0.0002135196,0.0003726771,0.0000222085,0.001510604,0.0005414838,0.000006421244],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003531903,"about_ca_system_score_gemma":0.00007643781,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001023244,"about_ca_topic_score_gemma":0.0007062231,"domain_scores_codex":[0.9969601,0.0007982828,0.0004270569,0.0005767423,0.0006395043,0.00059831],"domain_scores_gemma":[0.9979549,0.000119069,0.0002018712,0.001497536,0.00006848724,0.0001581139],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00005772484,0.0001727555,0.1810188,0.00002688045,0.00001441034,0.000002848387,0.00008887358,0.0001050533,0.8091166,0.00004279188,0.0003928748,0.008960331],"study_design_scores_gemma":[0.000480068,0.0002871852,0.5454268,0.00001862369,0.000008683751,0.000003660452,0.0001426197,0.0003500089,0.435666,0.00007578388,0.01739039,0.0001502162],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946286,0.0004862125,0.002839123,0.0003286982,0.000123467,0.0009395257,0.00007912675,0.000006499445,0.0005687179],"genre_scores_gemma":[0.9895717,0.0000681602,0.009739085,0.0001254587,0.0001876755,0.00007515401,0.0000445271,0.00003746958,0.000150775],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3734506,"threshold_uncertainty_score":0.7141533,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1393145659871479,"score_gpt":0.4504785492499677,"score_spread":0.3111639832628198,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}