{"id":"W2692754402","doi":"10.1111/1440-1681.12799","title":"A co‐drug conjugate of naringenin and lipoic acid mediates neuroprotection in a rat model of oxidative stress","year":2017,"lang":"en","type":"article","venue":"Clinical and Experimental Pharmacology and Physiology","topic":"Biochemical Acid Research Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; University of Prince Edward Island","funders":"Atlantic Canada Opportunities Agency","keywords":"Neuroprotection; Naringenin; Oxidative stress; Pharmacology; In vivo; Chemistry; Lipoic acid; Antioxidant; Glutathione; Biochemistry; Medicine; Biology; Flavonoid; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001705386,0.0001136687,0.000312196,0.00002156765,0.00009883568,0.000003953701,0.0001072127,0.0001412557,0.000006819074],"category_scores_gemma":[0.00009044971,0.00009287856,0.00003707306,0.00001271195,0.002275374,0.000007754819,0.0003485486,0.0001712759,2.577249e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000001756869,"about_ca_system_score_gemma":0.0000146866,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002539405,"about_ca_topic_score_gemma":0.000006585834,"domain_scores_codex":[0.999086,0.0001451377,0.0002600969,0.0003236443,0.00003588136,0.0001492461],"domain_scores_gemma":[0.9995878,0.00006063514,0.0001417854,0.000106287,0.00003170158,0.00007173889],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001572415,0.0002122383,0.006706729,0.00005190356,0.00006707601,0.000001107848,0.0001311871,0.000005722492,0.9907852,0.00001765863,0.00009705412,0.0003516444],"study_design_scores_gemma":[0.001798364,0.0007973321,0.006293637,0.00001021923,0.00001276309,0.000001925415,0.0001058649,0.0005166901,0.9900862,0.0002698572,0.00002322972,0.00008392861],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965767,0.002917427,0.000003866002,0.0001666016,0.00009065428,0.0001704793,0.00002738839,0.000002130228,0.00004469834],"genre_scores_gemma":[0.9968567,0.00279676,0.0000865253,0.0001137501,0.00007506089,0.00003422515,0.00001205894,0.000005375896,0.00001952774],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002176538,"threshold_uncertainty_score":0.8383709,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03607088547905019,"score_gpt":0.3923338271604746,"score_spread":0.3562629416814244,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}