{"id":"W2711933274","doi":"10.1016/j.bbapap.2017.06.017","title":"Recognizing asymmetry in pseudo-symmetry; structural insights into the interaction between amphipathic α-helices and X-bundle proteins","year":2017,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Helix bundle; Antiparallel (mathematics); Helix (gastropod); Bundle; Crystallography; Amphiphile; Protein structure; Biophysics; Chemistry; Biology; Physics; Biochemistry; Materials science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005913794,0.0008201614,0.001040401,0.001198265,0.0002617088,0.001094924,0.0009806377,0.001254038,0.001457205],"category_scores_gemma":[0.0005795722,0.0003345888,0.0002368924,0.001248579,0.00101872,0.002010827,0.0008567137,0.002001246,0.001481088],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006410021,"about_ca_system_score_gemma":0.0007493768,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006014965,"about_ca_topic_score_gemma":0.00107279,"domain_scores_codex":[0.9998714,0.00001644664,0.00001384978,0.00002466476,0.00005797576,0.00001575217],"domain_scores_gemma":[0.9998345,0.0000709222,0.0000346112,0.000005192484,0.00003502433,0.00001977084],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001031323,0.00005694531,0.0001322204,0.01398829,0.00006878578,0.0002999221,0.0001064894,0.0005434613,0.01376199,0.01369145,0.03298998,0.9242575],"study_design_scores_gemma":[0.00001716252,0.00004584195,0.0003393003,0.001125595,0.00004124916,0.0008888979,0.00004829377,0.0001211028,0.002697891,0.002892037,0.9917598,0.000022816],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002206075,0.9981031,0.0003869696,0.0002694773,0.0002549217,0.000004424754,0.00001385675,0.000009660038,0.000736903],"genre_scores_gemma":[0.0009723004,0.997499,0.0003543104,0.0002880375,0.0001951142,0.000005790811,0.00002750695,0.000002077192,0.0006557557],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001457205,"threshold_uncertainty_score":0.004874885,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05808046885034102,"score_gpt":0.3364134964154178,"score_spread":0.2783330275650768,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}