{"id":"W2724151621","doi":"10.1016/j.heliyon.2017.e00338","title":"Calcium-stimulated adenylyl cyclase subtype 1 (AC1) contributes to LTP in the insular cortex of adult mice","year":2017,"lang":"en","type":"article","venue":"Heliyon","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Long-term potentiation; Adenylyl cyclase; Neuroscience; Synaptic plasticity; Postsynaptic potential; Neurotransmission; Chemistry; LTP induction; Biology; Stimulation; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001379317,0.0006943184,0.0003707528,0.0007943038,0.0002218718,0.0003966138,0.0003260324,0.0003300517,0.002817395],"category_scores_gemma":[0.0001248241,0.0003404704,0.0002868103,0.0002239064,0.0005478841,0.0004292113,0.0002510893,0.001652334,0.0005973792],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006357754,"about_ca_system_score_gemma":0.000433454,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002075562,"about_ca_topic_score_gemma":0.003136111,"domain_scores_codex":[0.9998744,0.000005733748,0.00001031336,0.00003357813,0.00002663778,0.00004938307],"domain_scores_gemma":[0.9996868,0.00002039737,0.0001229069,0.00002212687,0.00002899001,0.0001188146],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003142856,0.00003025303,0.0002201202,0.00002603481,0.00000447986,0.00007822926,0.00001877814,0.00002152087,0.9981889,0.0001008321,0.00005710002,0.0009393253],"study_design_scores_gemma":[0.00008433512,0.0004493026,0.02547778,0.00002036162,0.00006772227,0.0004404955,0.0001013525,0.0006384648,0.9710711,0.0002218997,0.001416681,0.00001049285],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956436,0.0006453219,0.001024481,0.0002084018,0.00003822918,0.00001303178,0.0008061283,0.0001595796,0.001461335],"genre_scores_gemma":[0.9897611,0.0008599966,0.001199925,0.0001102324,0.00002236069,0.00005337455,0.0008328714,0.00009447913,0.007065638],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002817395,"threshold_uncertainty_score":0.009425104,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0640460997988478,"score_gpt":0.3745762324247702,"score_spread":0.3105301326259224,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}