{"id":"W2725030403","doi":"10.3233/jad-170337","title":"Capsaicin Attenuates Amyloid-β-Induced Synapse Loss and Cognitive Impairments in Mice","year":2017,"lang":"en","type":"article","venue":"Journal of Alzheimer s Disease","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Key Research and Development Program of China; Natural Science Foundation of Chongqing; Ministry of Science and Technology of the People's Republic of China; Chongqing Science and Technology Commission; National Natural Science Foundation of China","keywords":"Capsaicin; Synapse; Neuroscience; Amyloid β; Amyloid (mycology); Cognition; Dementia; Medicine; Psychology; Internal medicine; Disease; Pathology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003112539,0.0002598393,0.0005198903,0.0002735122,0.0002298104,0.0001067501,0.0001878128,0.00007073116,0.00009427738],"category_scores_gemma":[0.0004276294,0.0002001933,0.0002135026,0.00007989522,0.0002458502,0.0005333766,0.0001133536,0.0003398727,0.00004236569],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006007215,"about_ca_system_score_gemma":0.0005743374,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001725261,"about_ca_topic_score_gemma":0.00001315404,"domain_scores_codex":[0.9981029,0.0001024468,0.0004775707,0.000277659,0.0005935405,0.0004458948],"domain_scores_gemma":[0.9972691,0.00008193483,0.0004671045,0.0003179289,0.0003655689,0.001498396],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.005656742,0.002210847,0.9392028,0.00007278322,0.01358296,0.03006853,0.0002464578,6.077275e-7,0.0003863447,0.0000080272,0.0004607246,0.008103129],"study_design_scores_gemma":[0.0089474,0.0006841998,0.9818676,0.0006745417,0.00513337,0.0004084443,0.000216783,0.00005306337,0.001621261,0.0001977701,0.00001020349,0.0001853749],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9700028,0.0273366,0.000001475713,0.001812108,0.00009775862,0.0004774353,0.00006251204,0.000008790058,0.000200577],"genre_scores_gemma":[0.9990256,0.0004471933,0.00004126908,0.0002292142,0.000178196,0.00001524563,0.00001354464,0.00003198213,0.00001772347],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04266474,"threshold_uncertainty_score":0.8163647,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03736424401371415,"score_gpt":0.3490139385255244,"score_spread":0.3116496945118103,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}