{"id":"W2725255062","doi":"10.2196/ijmr.7612","title":"Toward a New Kind of Vaccine: A Logical Extension of the Symmetrical Immune Network Theory","year":2017,"lang":"en","type":"article","venue":"Interactive Journal of Medical Research","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; University of British Columbia Hospital; University of Toronto","funders":"","keywords":"Antibody; Antigen; Immunology; Toxoid; Immune system; Immunization; Idiotype; Biology; Monoclonal antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.007037358,0.0001562237,0.0007499465,0.0002687599,0.0003013336,0.00002379564,0.002487603,0.0005603187,0.003023075],"category_scores_gemma":[0.02310762,0.00008253269,0.0004136829,0.0002718892,0.001359317,0.0001376363,0.001322375,0.003538563,0.00006123981],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007055653,"about_ca_system_score_gemma":0.0007358933,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002938415,"about_ca_topic_score_gemma":0.00001101262,"domain_scores_codex":[0.9953043,0.002285185,0.000990142,0.0002139777,0.0006727487,0.0005336604],"domain_scores_gemma":[0.9921679,0.005033515,0.001037397,0.0006419055,0.001002564,0.0001167172],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007530149,0.000951366,0.002415595,0.00003430302,0.0008407863,0.0001861913,0.0006769287,0.000002867683,0.8604537,0.004819852,0.0233019,0.09878638],"study_design_scores_gemma":[0.01267078,0.00636202,0.1298666,0.003290298,0.0002187405,0.003533084,0.002390896,0.00003182532,0.7394917,0.03260226,0.0691935,0.000348273],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9680148,0.0135552,0.0007788445,0.01263618,0.002684122,0.0002351787,0.000004161239,0.0000046665,0.002086817],"genre_scores_gemma":[0.997131,0.001154407,0.00005382409,0.0000808758,0.000275351,0.000001708114,0.00000100604,0.00001176181,0.001290104],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.127451,"threshold_uncertainty_score":0.9987603,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06944231409279239,"score_gpt":0.3877753602206802,"score_spread":0.3183330461278878,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}