{"id":"W2725943383","doi":"10.1016/j.mce.2017.07.007","title":"Immunosuppression with tacrolimus improved implantation and rescued expression of uterine progesterone receptor and its co-regulators FKBP52 and PIASy at nidation in the obese and diabetic mice: Comparative studies with metformin","year":2017,"lang":"en","type":"article","venue":"Molecular and Cellular Endocrinology","topic":"Reproductive System and Pregnancy","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; Queen's University","keywords":"Tacrolimus; Immunosuppression; Medicine; Metformin; Endocrinology; Internal medicine; Diabetes mellitus; Downregulation and upregulation; Transplantation; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001775007,0.0002216495,0.000444932,0.00008053205,0.0003386754,0.0000287937,0.00008772878,0.0001005296,0.000003786206],"category_scores_gemma":[0.00002563831,0.0001322764,0.00001241062,0.00003195884,0.0006463806,0.0001606035,0.0001812645,0.000138462,6.022238e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009267126,"about_ca_system_score_gemma":0.0000101012,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004243636,"about_ca_topic_score_gemma":0.000036991,"domain_scores_codex":[0.9986621,0.0003680119,0.0002356148,0.0004498648,0.00004286257,0.000241587],"domain_scores_gemma":[0.9992957,0.00007729511,0.0002519843,0.0002871988,0.00006605057,0.00002180832],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007186583,0.00003560462,0.0193966,0.0002633082,0.0001312166,0.00005496328,0.004090125,3.378201e-7,0.9742532,0.0001181043,0.000006095941,0.0009317847],"study_design_scores_gemma":[0.003136229,0.0008718877,0.06245447,0.0002412717,0.00007198159,0.001107105,0.001715229,0.000004607768,0.9300292,0.0000448499,0.0001569508,0.0001662177],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9388418,0.06017095,0.00003271492,0.0001169824,0.00004651778,0.0007292295,0.00002142753,0.000008072052,0.00003230754],"genre_scores_gemma":[0.9984507,0.001167469,0.00009626817,0.00001080005,0.000006285414,0.00008522584,0.00004960229,0.00001103292,0.0001226421],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05960888,"threshold_uncertainty_score":0.5394074,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01905449488232357,"score_gpt":0.2884433638267175,"score_spread":0.2693888689443939,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}