{"id":"W2726145815","doi":"10.1007/s00011-017-1074-y","title":"The critical role of macrophages in the pathogenesis of hidradenitis suppurativa","year":2017,"lang":"en","type":"review","venue":"Inflammation Research","topic":"Hidradenitis Suppurativa and Treatments","field":"Medicine","cited_by":83,"is_retracted":false,"has_abstract":false,"ca_institutions":"Sunnybrook Health Science Centre; Sunnybrook Hospital; University of Toronto","funders":"","keywords":"Immunology; Inflammation; Pathogenesis; Medicine; Inflammasome; Hidradenitis suppurativa; Macrophage; Immune system; TLR2; Downregulation and upregulation; Cytokine; Population; Proinflammatory cytokine; Immune dysregulation; Interleukin 23; Innate immune system; Disease; Interleukin 17; Biology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002421329,0.0002331523,0.00104484,0.000380654,0.0003831278,0.000101485,0.0006926711,0.0002620175,0.0001216511],"category_scores_gemma":[0.003313629,0.0001159484,0.0003281949,0.0004363938,0.0008848154,0.000127605,0.0001280838,0.0006880006,0.00008797827],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009599316,"about_ca_system_score_gemma":0.0006936767,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000107364,"about_ca_topic_score_gemma":0.00005919591,"domain_scores_codex":[0.9952525,0.001813868,0.0009564699,0.000261767,0.001309571,0.0004057745],"domain_scores_gemma":[0.9937248,0.004321545,0.0002930847,0.001046802,0.0005384687,0.00007530888],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003515138,0.0001009958,0.0001336051,0.005269866,0.0001016392,0.004066504,0.0006999762,6.658307e-9,0.0001058986,0.003476032,0.00009788221,0.9859124],"study_design_scores_gemma":[0.0007407307,0.0004780593,0.00109085,0.01324056,0.0004481725,0.01158173,0.001312437,0.00001162088,0.0005180092,0.001748865,0.9686155,0.0002134652],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003423592,0.9874076,0.000001245951,0.005116921,0.00005616232,0.001911185,0.0001181447,0.00000760757,0.00503883],"genre_scores_gemma":[0.1500069,0.8487189,0.00004004976,2.656169e-7,0.000154183,0.0004251122,0.00008448884,0.00002733823,0.0005427743],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.985699,"threshold_uncertainty_score":0.4728237,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.274028611414713,"score_gpt":0.5414166135399971,"score_spread":0.2673880021252842,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}