{"id":"W2726483806","doi":"10.3390/molecules22071124","title":"Substituted Caffeic and Ferulic Acid Phenethyl Esters: Synthesis, Leukotrienes Biosynthesis Inhibition, and Cytotoxic Activity","year":2017,"lang":"en","type":"article","venue":"Molecules","topic":"Essential Oils and Antimicrobial Activity","field":"Agricultural and Biological Sciences","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Moncton","funders":"Natural Sciences and Engineering Research Council of Canada; Beatrice Hunter Cancer Research Institute; New Brunswick Innovation Foundation; Brain Tumour Foundation of Canada; Université de Moncton; Cancer Research Institute","keywords":"Caffeic acid phenethyl ester; Caffeic acid; Chemistry; Cytotoxicity; Ferulic acid; Biochemistry; Docking (animal); Arachidonate 5-lipoxygenase; Enzyme; Polyphenol; Stereochemistry; Antioxidant; In vitro; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001428321,0.0005496397,0.0002666565,0.0003512597,0.0001618093,0.0001472904,0.0002421028,0.0002451384,0.0009531311],"category_scores_gemma":[0.0001345808,0.0001122212,0.0002879679,0.0003071615,0.0001486252,0.0003416805,0.0001753648,0.0002974187,0.0002929885],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002518189,"about_ca_system_score_gemma":0.0002620756,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008919036,"about_ca_topic_score_gemma":0.001467545,"domain_scores_codex":[0.9999609,0.000005542438,0.000003726941,0.000007232846,0.000008264275,0.00001439709],"domain_scores_gemma":[0.9999582,0.000004172301,0.00001143663,0.000004616713,0.000006959855,0.00001468507],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003475452,0.0001375445,0.0002347418,0.0005167311,0.00002794534,0.0004071695,0.00005206781,0.0006905713,0.9716489,0.0006178829,0.0001664091,0.02515264],"study_design_scores_gemma":[0.00007729322,0.001394159,0.002062711,0.00003382518,0.00007004938,0.0004483643,0.00002044177,0.0004620921,0.979104,0.0001918686,0.01611588,0.00001932087],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9127147,0.06671763,0.01131807,0.0004384363,0.00009402719,0.0002576789,0.001000713,0.00009224188,0.007366589],"genre_scores_gemma":[0.9613705,0.02896081,0.005702186,0.0000937493,0.00004910615,0.00005386302,0.0004714078,0.00001771754,0.003280732],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009531311,"threshold_uncertainty_score":0.00318855,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01667990693865815,"score_gpt":0.214722982499803,"score_spread":0.1980430755611448,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}