{"id":"W2726483806","doi":"10.3390/molecules22071124","title":"Substituted Caffeic and Ferulic Acid Phenethyl Esters: Synthesis, Leukotrienes Biosynthesis Inhibition, and Cytotoxic Activity","year":2017,"lang":"en","type":"article","venue":"Molecules","topic":"Essential Oils and Antimicrobial Activity","field":"Agricultural and Biological Sciences","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Moncton","funders":"Natural Sciences and Engineering Research Council of Canada; Beatrice Hunter Cancer Research Institute; New Brunswick Innovation Foundation; Brain Tumour Foundation of Canada; Université de Moncton; Cancer Research Institute","keywords":"Caffeic acid phenethyl ester; Caffeic acid; Chemistry; Cytotoxicity; Ferulic acid; Biochemistry; Docking (animal); Arachidonate 5-lipoxygenase; Enzyme; Polyphenol; Stereochemistry; Antioxidant; In vitro; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001208226,0.0001881212,0.0002331327,0.00001377593,0.000894703,0.0004220459,0.0001492005,0.0001111294,0.00003146689],"category_scores_gemma":[0.0001493253,0.00008547576,0.0000590177,0.00005625167,0.0003174785,0.0003711699,0.0001613943,0.00008256148,0.000006983834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001070284,"about_ca_system_score_gemma":0.00000683406,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007038957,"about_ca_topic_score_gemma":0.001219649,"domain_scores_codex":[0.9990867,0.00007133906,0.0001086519,0.0003826792,0.0001082913,0.0002422723],"domain_scores_gemma":[0.999485,0.0001315262,0.0001318212,0.0001069134,0.00003256264,0.0001121788],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002563507,0.00005746057,0.002298112,0.0000176163,0.0000127686,0.00001317504,0.00001780835,1.255134e-7,0.9458941,0.00007531782,0.00001997886,0.05156793],"study_design_scores_gemma":[0.00007749621,0.0000284718,0.1917046,0.0000566219,0.00002220283,0.00001272203,0.00002071323,0.00001500082,0.8075168,0.0001373485,0.0002227752,0.0001852928],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969448,0.0002106586,0.0000138466,0.002352909,0.00005435368,0.0001220525,0.00005905307,0.00005034201,0.0001919198],"genre_scores_gemma":[0.9993472,0.0003767796,0.00006495421,0.00006796678,0.0001019226,0.00001210779,0.00000572455,0.000001934748,0.00002147831],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1894065,"threshold_uncertainty_score":0.6881423,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01667990693865815,"score_gpt":0.214722982499803,"score_spread":0.1980430755611448,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}