{"id":"W2726533663","doi":"","title":"Molecular mechanisms of protection by dietary polyphenols against free fatty acid-induced mitochondrial dysfunction and endoplasmic reticulum stress in an in vitro model of non-alcoholic fatty liver disease","year":2017,"lang":"en","type":"dissertation","venue":"University Library - University of Saskatchewan (University of Saskatchewan)","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Saskatchewan Health Research Foundation","keywords":"Endoplasmic reticulum; Fatty liver; In vitro; Fatty acid; Polyphenol; Chemistry; Mitochondrion; Biochemistry; Disease; Unfolded protein response; Medicine; Internal medicine; Antioxidant","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001926995,0.0003012231,0.0002599281,0.0002440054,0.0002135971,0.0002902237,0.0002098435,0.0003210173,0.001415267],"category_scores_gemma":[0.00008309523,0.0001634228,0.0004516209,0.0001827257,0.0001695129,0.000211723,0.000137441,0.0005707518,0.0002523712],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004236214,"about_ca_system_score_gemma":0.0004942008,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002120266,"about_ca_topic_score_gemma":0.003640398,"domain_scores_codex":[0.9999338,0.00001396432,0.000004606261,0.0000078311,0.00001054334,0.00002924141],"domain_scores_gemma":[0.999939,0.000009482224,0.00001178285,0.000008213901,0.00001899853,0.00001255246],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001282531,0.0001974172,0.0002805937,0.0002203576,0.00004295021,0.0001268173,0.00003550396,0.00008877458,0.993006,0.0003839268,0.0002030056,0.0041322],"study_design_scores_gemma":[0.0002768211,0.001184609,0.0198593,0.00007741596,0.0002215744,0.0002860194,0.0001639163,0.0005589579,0.9727147,0.0003739165,0.004266384,0.00001646028],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9779817,0.014953,0.001914052,0.0006482482,0.0001626495,0.00009267815,0.0005260172,0.00004439158,0.00367716],"genre_scores_gemma":[0.9797921,0.01115567,0.001576622,0.0002145915,0.00002679859,0.00007607594,0.0006619824,0.00001313624,0.006482959],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002120266,"threshold_uncertainty_score":0.004734516,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01054660656357399,"score_gpt":0.1898793293576333,"score_spread":0.1793327227940593,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}