{"id":"W2726845895","doi":"10.1182/blood.v128.22.901.901","title":"SWOG S1203: A Randomized Phase III Study of Standard Cytarabine Plus Daunorubicin (7+3) Therapy Versus Idarubicin with High Dose Cytarabine (IA) with or without Vorinostat (IA+V) in Younger Patients with Previously Untreated Acute Myeloid Leukemia (AML)","year":2016,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Idarubicin; Medicine; Internal medicine; Cytarabine; Vorinostat; Oncology; Clinical endpoint; Gastroenterology; Transplantation; Randomized controlled trial; Chemotherapy; Histone deacetylase; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.001329997,0.001328996,0.004206803,0.0009323589,0.000189329,0.00007262798,0.0006648581,0.0003061708,0.000320446],"category_scores_gemma":[0.0002645593,0.0006202186,0.0001855275,0.001978135,0.0009365072,0.0006407801,0.0001895124,0.0008766159,0.0000203903],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001639347,"about_ca_system_score_gemma":0.003550103,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004384777,"about_ca_topic_score_gemma":0.002730667,"domain_scores_codex":[0.9915549,0.0008453161,0.001629199,0.001666036,0.002699398,0.001605125],"domain_scores_gemma":[0.994231,0.0008865639,0.000903382,0.001906761,0.001390503,0.0006818193],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9012208,0.007066591,0.07043672,0.0001343432,0.006455069,0.001838568,0.003603934,0.00004478778,0.005589579,0.00001460617,0.00008000442,0.00351497],"study_design_scores_gemma":[0.891652,0.07148793,0.01166449,0.001340525,0.003341214,0.0001200642,0.0009539211,0.00006990576,0.01839763,0.000004483673,0.00007268148,0.0008951545],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9834616,0.0002613962,0.0002694447,0.0002760594,0.00009242392,0.01494114,0.0002334118,0.0002388278,0.0002257011],"genre_scores_gemma":[0.9944314,0.0006989776,0.001710086,0.0001218918,0.0001419792,0.001123221,0.0002311991,0.0003190197,0.001222178],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06442133,"threshold_uncertainty_score":0.9999461,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01548724003329259,"score_gpt":0.2988562247141778,"score_spread":0.2833689846808852,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}