{"id":"W2726845895","doi":"10.1182/blood.v128.22.901.901","title":"SWOG S1203: A Randomized Phase III Study of Standard Cytarabine Plus Daunorubicin (7+3) Therapy Versus Idarubicin with High Dose Cytarabine (IA) with or without Vorinostat (IA+V) in Younger Patients with Previously Untreated Acute Myeloid Leukemia (AML)","year":2016,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Idarubicin; Medicine; Internal medicine; Cytarabine; Vorinostat; Oncology; Clinical endpoint; Gastroenterology; Transplantation; Randomized controlled trial; Chemotherapy; Histone deacetylase; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003239772,0.002118876,0.002455665,0.000551586,0.0004506039,0.001167937,0.0011893,0.001484593,0.005933175],"category_scores_gemma":[0.001705201,0.0007994838,0.001915302,0.000575572,0.001549896,0.0008573515,0.0005111001,0.003847556,0.001035307],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001155535,"about_ca_system_score_gemma":0.002375292,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001429111,"about_ca_topic_score_gemma":0.003018965,"domain_scores_codex":[0.9992136,0.0005035156,0.00003664517,0.00009880601,0.00005812585,0.000089289],"domain_scores_gemma":[0.9986537,0.0002859467,0.0002749254,0.00009219279,0.00007207876,0.0006213291],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9605638,0.02000645,0.0007298063,0.0003196555,0.0006243555,0.00003502454,0.00006422834,0.0005611865,0.00415658,0.0001753904,0.0008358971,0.0119277],"study_design_scores_gemma":[0.8548994,0.1418413,0.001199838,0.00001684879,0.0002986524,0.0000315586,0.00002207429,0.0006239227,0.0004346394,0.0001495716,0.0004683792,0.00001389199],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909526,0.0008846425,0.0005970335,0.0004916972,0.0003724883,0.004566452,0.0008762702,0.00008757576,0.001171225],"genre_scores_gemma":[0.9801065,0.00166055,0.002767272,0.001419681,0.0003785776,0.008094338,0.001921963,0.00004949923,0.003601637],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005933175,"threshold_uncertainty_score":0.01984841,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01548724003329259,"score_gpt":0.2988562247141778,"score_spread":0.2833689846808852,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}