{"id":"W2728845318","doi":"10.1182/blood.v128.22.1375.1375","title":"Platelet Release from Infused CD34+-Derived Human Megakaryocytes: Lessons from a Natural-Occurring Platelet Bioreactor","year":2016,"lang":"en","type":"article","venue":"Blood","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Platelet; Thrombopoiesis; Megakaryocyte; In vivo; In vitro; Cell biology; Bone marrow; Biology; Pathology; Chemistry; Immunology; Haematopoiesis; Stem cell; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004006175,0.0001883848,0.0002318866,0.0001237255,0.0001236531,0.0006210305,0.0004631414,0.0004120432,0.0006724377],"category_scores_gemma":[0.0003232142,0.0001030771,0.0002279435,0.00006705681,0.0003026873,0.000317629,0.0002889564,0.0009084057,0.0003443627],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002796126,"about_ca_system_score_gemma":0.0001309944,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001422085,"about_ca_topic_score_gemma":0.0001683099,"domain_scores_codex":[0.9998679,0.00003168711,0.000007639492,0.00002408298,0.00005377046,0.0000148538],"domain_scores_gemma":[0.9998674,0.00005483975,0.00001998657,0.00001413032,0.0000245674,0.00001904771],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000121436,0.000132714,0.0003711429,0.0002517847,0.00001298232,0.0003811283,0.0001010969,0.0006604668,0.9744601,0.002107204,0.000601713,0.02079817],"study_design_scores_gemma":[0.00004268806,0.0006292992,0.001596142,0.00004291067,0.00002855552,0.0009221144,0.00005593661,0.0046025,0.9791582,0.0009205455,0.01198695,0.00001403619],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8401749,0.04729786,0.09862558,0.00365914,0.0006424073,0.0001025166,0.0002419201,0.0005457758,0.008709786],"genre_scores_gemma":[0.960095,0.01480135,0.02145218,0.0005242057,0.0002129472,0.0000515121,0.0001696179,0.00008700178,0.002606209],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006724377,"threshold_uncertainty_score":0.002249479,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02023446305354764,"score_gpt":0.2708246640666567,"score_spread":0.2505902010131091,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}