{"id":"W2729589316","doi":"10.1016/j.compbiolchem.2017.10.011","title":"Designing anti-Zika virus peptides derived from predicted human-Zika virus protein-protein interactions","year":2017,"lang":"en","type":"article","venue":"Computational Biology and Chemistry","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"Agriculture and Agri-Food Canada; University of Regina; Carleton University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Zika virus; Biology; Computational biology; Virology; Virus; Mechanism (biology); Human pathogen; Bioinformatics; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005841806,0.0001872854,0.0003053258,0.00002307603,0.0006187322,0.0000669747,0.0001571057,0.000153658,0.0004318964],"category_scores_gemma":[0.000168338,0.0001736716,0.000092484,0.00002385163,0.0002934352,0.00008374185,0.00009435985,0.0002428608,0.00001471596],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002667595,"about_ca_system_score_gemma":0.0001011496,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001369073,"about_ca_topic_score_gemma":0.000006988417,"domain_scores_codex":[0.9990189,0.0000326897,0.0002542046,0.000396913,0.00009587068,0.0002014395],"domain_scores_gemma":[0.9991326,0.0000762083,0.0002132869,0.0002820722,0.0001407492,0.0001550459],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001943551,0.0001307556,0.01195894,0.00005435034,0.0002027961,0.00002776489,0.00003802253,0.00002086915,0.9854616,0.0001072337,0.0001135528,0.001689749],"study_design_scores_gemma":[0.003750734,0.000149641,0.3401532,0.0004105188,0.0002577219,0.000041706,0.0001241789,0.002551001,0.6419373,0.009413515,0.0008144855,0.0003959524],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944397,0.0005370384,0.003173649,0.0004617578,0.00005535595,0.0002964318,0.0002496301,0.00007042634,0.0007159754],"genre_scores_gemma":[0.9966799,0.00001015398,0.001296442,0.000175241,0.000406607,0.00009763742,0.0009505893,0.0000147389,0.0003686974],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3435243,"threshold_uncertainty_score":0.7082124,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01963104574886333,"score_gpt":0.3110379511058833,"score_spread":0.29140690535702,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}