{"id":"W2731009462","doi":"10.1158/1078-0432.ccr-17-0790","title":"Cancer Screening Recommendations and Clinical Management of Inherited Gastrointestinal Cancer Syndromes in Childhood","year":2017,"lang":"en","type":"review","venue":"Clinical Cancer Research","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":128,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; McGill University; McGill Genome Centre; Hospital for Sick Children","funders":"National Institutes of Health; National Institute for Health and Care Research","keywords":"Medicine; Cancer; Gastrointestinal cancer; Childhood cancer; Intensive care medicine; Internal medicine; Colorectal cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.005980283,0.0005711535,0.003790827,0.0006143128,0.0002226858,0.00007893616,0.0009193268,0.0006149057,0.001488942],"category_scores_gemma":[0.001498739,0.000479373,0.0007866764,0.0008784502,0.001578639,0.00008827952,0.00118504,0.004419884,0.00001671265],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006467874,"about_ca_system_score_gemma":0.002887581,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002391133,"about_ca_topic_score_gemma":0.001903056,"domain_scores_codex":[0.9917112,0.001432774,0.00315454,0.001544821,0.001132625,0.001024057],"domain_scores_gemma":[0.994038,0.002377851,0.001020468,0.001315788,0.0006188315,0.0006289983],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002332921,0.0004417237,0.06169216,0.01009577,0.0008167672,0.0001342866,0.00002082987,0.000001168561,1.59472e-7,0.000008569978,0.003435074,0.9231202],"study_design_scores_gemma":[0.002596915,0.001001071,0.1698076,0.174109,0.001208393,0.0000775123,0.00006593979,0.00002878346,5.011269e-7,0.000034204,0.6506494,0.000420681],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005912699,0.9872712,0.000009898366,0.001540867,0.0009350327,0.003208237,0.0003617114,0.00003417293,0.000726167],"genre_scores_gemma":[0.001219634,0.9915936,0.002743317,0.00009005967,0.0008328072,0.00191718,0.00006921762,0.0001362717,0.001397894],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9226995,"threshold_uncertainty_score":0.9997658,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.6863700664617289,"score_gpt":0.6628334277154109,"score_spread":0.02353663874631806,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}