{"id":"W27323823","doi":"10.1023/a:1026585006064","title":"Signaling through sphingolipid microdomains of the plasma membrane: The concept of signaling platform","year":2000,"lang":"en","type":"review","venue":"Glycoconjugate Journal","topic":"Caveolin-1 and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":94,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Cell biology; Signal transduction; Signal transducing adaptor protein; Biology; Phosphorylation; Cell signaling; Receptor tyrosine kinase; Receptor; Tyrosine kinase; Cell surface receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006474326,0.0005143946,0.001201781,0.00006107792,0.0003425564,0.00007299437,0.00126622,0.0004798897,0.0001969001],"category_scores_gemma":[0.0001150289,0.0002831536,0.001353597,0.0002774695,0.0004281042,0.0000138616,0.0002171806,0.0008404204,0.000006872379],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003154843,"about_ca_system_score_gemma":0.0008153403,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001486294,"about_ca_topic_score_gemma":0.000006246656,"domain_scores_codex":[0.9971859,0.0002124455,0.001371186,0.0003658507,0.0004191453,0.00044547],"domain_scores_gemma":[0.9972944,0.0001386078,0.001657318,0.0006277914,0.0001948432,0.00008704142],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000665529,0.0005382115,0.00001275051,0.02039812,0.005287433,0.00008965019,0.002906154,0.002118665,0.3212571,0.00063835,0.004183275,0.6419048],"study_design_scores_gemma":[0.0004719039,0.000110602,1.2149e-7,0.003132769,0.0006501625,0.001040579,0.0001510044,0.000002378209,0.2176365,0.0001013148,0.7764218,0.0002808399],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01407836,0.9835362,0.0001414317,0.00003417777,0.0005117781,0.0005217434,0.0001292784,0.000006080814,0.001040944],"genre_scores_gemma":[0.0128739,0.9849432,0.0001490788,0.0001046117,0.001320641,0.00001352896,0.00007311315,0.00007932126,0.0004426696],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7722386,"threshold_uncertainty_score":0.9999621,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02499123290116601,"score_gpt":0.2758243855316611,"score_spread":0.250833152630495,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}