{"id":"W2732486120","doi":"10.1016/j.molmed.2017.06.003","title":"Amylin Receptor: A Potential Therapeutic Target for Alzheimer’s Disease","year":2017,"lang":"en","type":"review","venue":"Trends in Molecular Medicine","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta; Women and Children’s Health Research Institute","funders":"Canadian Institutes of Health Research; University Hospital Foundation","keywords":"Amylin; Neuroscience; Senile plaques; Disease; Genetically modified mouse; Receptor; Amyloid (mycology); Mediator; Alzheimer's disease; Extracellular; Medicine; Transgene; Biology; Internal medicine; Endocrinology; Cell biology; Pathology; Biochemistry; Diabetes mellitus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004898107,0.0007867035,0.001451528,0.001354855,0.0002040659,0.00111773,0.0006519402,0.00103793,0.0040898],"category_scores_gemma":[0.0005197134,0.0002186699,0.0004280981,0.001419757,0.0004583621,0.001350023,0.000727826,0.002124146,0.00256365],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004283107,"about_ca_system_score_gemma":0.0009129155,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004908642,"about_ca_topic_score_gemma":0.001141647,"domain_scores_codex":[0.9998659,0.00001668965,0.00002182182,0.00002195999,0.00005463795,0.00001904118],"domain_scores_gemma":[0.9998289,0.00005889776,0.00004209803,0.000004793651,0.00004200491,0.0000233657],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000210503,0.00008927627,0.0001847642,0.01502162,0.0001282467,0.0003600525,0.00004355919,0.0002306022,0.003883397,0.003523654,0.03846829,0.937856],"study_design_scores_gemma":[0.00008883298,0.000172396,0.0007156307,0.002317419,0.0002330955,0.001338807,0.00006230928,0.0001007714,0.0007729434,0.002215608,0.9919587,0.00002336944],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002091844,0.9976467,0.0001411591,0.0005299439,0.0003066638,0.000004626208,0.00003412537,0.00001060133,0.001116895],"genre_scores_gemma":[0.0009622809,0.9975674,0.0001587222,0.0003124209,0.0002065039,0.000005402582,0.00004640782,0.000001438294,0.0007395171],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0040898,"threshold_uncertainty_score":0.01368177,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1480549730406913,"score_gpt":0.4546070282385635,"score_spread":0.3065520551978722,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}