{"id":"W2732486120","doi":"10.1016/j.molmed.2017.06.003","title":"Amylin Receptor: A Potential Therapeutic Target for Alzheimer’s Disease","year":2017,"lang":"en","type":"review","venue":"Trends in Molecular Medicine","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta; Women and Children’s Health Research Institute","funders":"Canadian Institutes of Health Research; University Hospital Foundation","keywords":"Amylin; Neuroscience; Senile plaques; Disease; Genetically modified mouse; Receptor; Amyloid (mycology); Mediator; Alzheimer's disease; Extracellular; Medicine; Transgene; Biology; Internal medicine; Endocrinology; Cell biology; Pathology; Biochemistry; Diabetes mellitus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005071964,0.0009372564,0.003169317,0.001145082,0.000172544,0.00003582327,0.000565964,0.0003902006,0.001159953],"category_scores_gemma":[0.0002283199,0.0006530915,0.001276475,0.0004351244,0.0004737159,0.0000699647,0.0001228355,0.0006724274,0.0001260205],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002223654,"about_ca_system_score_gemma":0.0009129592,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004317875,"about_ca_topic_score_gemma":0.000003193968,"domain_scores_codex":[0.9956577,0.0002977113,0.0009602974,0.001096833,0.001004111,0.0009833308],"domain_scores_gemma":[0.9963141,0.0001213565,0.000469977,0.00171119,0.0001457494,0.001237645],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004915709,0.0005708692,0.00002569318,0.003466074,0.01244558,0.002577769,0.00001888011,5.193707e-7,0.000001843307,0.0001169407,0.003080604,0.9772037],"study_design_scores_gemma":[0.005863503,0.001069244,0.0001264916,0.01371028,0.02616478,0.00006825695,0.000008656461,0.00005096589,0.00000350989,0.0004218253,0.9519489,0.0005635947],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000002532017,0.9938091,0.0002308167,0.001392151,0.0004197074,0.002301069,0.0003620693,0.00008025966,0.00140227],"genre_scores_gemma":[0.0006089163,0.9886629,0.0006923476,0.0002177141,0.0007639439,0.001320509,0.006885023,0.0002331181,0.0006155245],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.97664,"threshold_uncertainty_score":0.9997531,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1480549730406913,"score_gpt":0.4546070282385635,"score_spread":0.3065520551978722,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}