{"id":"W2732609911","doi":"10.1097/dss.0000000000001206","title":"Injectable DaxibotulinumtoxinA for the Treatment of Glabellar Lines: A Phase 2, Randomized, Dose-Ranging, Double-Blind, Multicenter Comparison With OnabotulinumtoxinA and Placebo","year":2017,"lang":"en","type":"article","venue":"Dermatologic Surgery","topic":"Botulinum Toxin and Related Neurological Disorders","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Canadian Institute of Mining, Metallurgy and Petroleum; McMaster University; University of Toronto; University of British Columbia","funders":"","keywords":"Medicine; Placebo; Double blind; Randomized controlled trial; Botulinum toxin; Multicenter study; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002944863,0.002486438,0.003126493,0.0007672459,0.0005230483,0.001231986,0.001158625,0.002328065,0.006984042],"category_scores_gemma":[0.001798552,0.001166647,0.002018105,0.000531285,0.001326693,0.001415732,0.0004366425,0.002478277,0.00100151],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00077495,"about_ca_system_score_gemma":0.001218681,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006337439,"about_ca_topic_score_gemma":0.001140812,"domain_scores_codex":[0.9988495,0.0005858131,0.00007453775,0.0002234982,0.0001271599,0.0001395023],"domain_scores_gemma":[0.9988276,0.0002951041,0.0003949456,0.00009358121,0.0001156254,0.00027305],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9666408,0.01792828,0.0002837538,0.0004714942,0.0004372713,0.00001911253,0.00004734757,0.0001306725,0.006128263,0.00006839717,0.000268426,0.007576154],"study_design_scores_gemma":[0.850643,0.1467299,0.0008867034,0.00002318194,0.0002937026,0.00001927986,0.00001539931,0.0002564871,0.000763762,0.0000567907,0.0003003816,0.00001136108],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9867823,0.003210966,0.0008505356,0.000365489,0.0005625663,0.006173756,0.0007738339,0.0001135804,0.001166894],"genre_scores_gemma":[0.9777499,0.003582767,0.003067409,0.0008847806,0.0008824766,0.009302136,0.0009878597,0.00004930022,0.003493453],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006984042,"threshold_uncertainty_score":0.02336401,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07105307323617767,"score_gpt":0.3460696701188699,"score_spread":0.2750165968826922,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}