{"id":"W2732727310","doi":"10.1136/annrheumdis-2017-211313","title":"Evaluation of the effect of baseline MRI sacroiliitis and C reactive protein status on etanercept treatment response in non-radiographic axial spondyloarthritis: a post hoc analysis of the EMBARK study","year":2017,"lang":"en","type":"letter","venue":"Annals of the Rheumatic Diseases","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"inVentiv Health Clinical","funders":"Pfizer","keywords":"Medicine; Etanercept; Sacroiliitis; Internal medicine; Post-hoc analysis; Sacroiliac joint; C-reactive protein; Placebo; Magnetic resonance imaging; BASDAI; Ankylosing spondylitis; Gastroenterology; Physical therapy; Surgery; Tumor necrosis factor alpha; Arthritis; Inflammation; Radiology; Pathology; Psoriatic arthritis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008806954,0.0007004093,0.002374946,0.0002244057,0.0005190055,0.001166701,0.0007260044,0.001513709,0.002561146],"category_scores_gemma":[0.0156707,0.000325713,0.002413015,0.0005035045,0.0006269902,0.0009657256,0.0003491915,0.002420143,0.0005253532],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005395506,"about_ca_system_score_gemma":0.0009566967,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001219701,"about_ca_topic_score_gemma":0.003219265,"domain_scores_codex":[0.9946688,0.003975784,0.0003762441,0.00039172,0.0003115576,0.0002757906],"domain_scores_gemma":[0.9802438,0.01456263,0.001522573,0.001439798,0.001274461,0.0009567823],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7075052,0.002383844,0.2191167,0.0007635548,0.01638709,0.002110721,0.0004718432,0.0006370674,0.002513468,0.0002751577,0.009721245,0.03811408],"study_design_scores_gemma":[0.1241805,0.09282961,0.725283,0.0002878582,0.03165364,0.002055786,0.001008953,0.004684098,0.004205982,0.001141213,0.01246301,0.0002062357],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897423,0.002361785,0.0003325856,0.003876183,0.000668334,0.0001629619,0.001101195,0.00002837774,0.001726414],"genre_scores_gemma":[0.9929528,0.0004974261,0.0006073002,0.002088938,0.0009427126,0.000225355,0.0006777606,0.00001537345,0.001992397],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008806954,"threshold_uncertainty_score":0.0465762,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02753027115743989,"score_gpt":0.3317270622820487,"score_spread":0.3041967911246088,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}