{"id":"W2733078953","doi":"10.3389/fimmu.2017.00776","title":"Apoptosis Induced via Gamma Delta T Cell Antigen Receptor “Blocking” Antibodies: A Cautionary Tale","year":2017,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"University of Alberta; Alberta Cancer Foundation; Alberta Innovates; Cancer Research Society","keywords":"Cytotoxicity; Monoclonal antibody; Apoptosis; Receptor; Blocking antibody; clone (Java method); T-cell receptor; Molecular biology; Antigen; Biology; Antibody; Cell culture; Cell biology; Chemistry; T cell; Cancer research; Immunology; In vitro; Biochemistry; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003677819,0.001098949,0.001130773,0.000597092,0.0009073958,0.001857219,0.001809595,0.002438983,0.001969912],"category_scores_gemma":[0.004545546,0.0003838262,0.0009065273,0.0004818286,0.002417886,0.002616028,0.0009483281,0.009512731,0.001536401],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000781037,"about_ca_system_score_gemma":0.0005490912,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007163566,"about_ca_topic_score_gemma":0.001504196,"domain_scores_codex":[0.9984334,0.0006569912,0.0001819993,0.0001792724,0.0004233797,0.0001249367],"domain_scores_gemma":[0.9974528,0.001315524,0.0001721137,0.0004149997,0.0005473051,0.00009733492],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001467044,0.0007553999,0.003372156,0.003596625,0.0004561407,0.006206818,0.001336203,0.002350291,0.5339093,0.03882084,0.1878212,0.219908],"study_design_scores_gemma":[0.0001958592,0.001832174,0.003618924,0.000582306,0.0003338996,0.009112313,0.0007446625,0.002662539,0.2890742,0.02776277,0.6638701,0.0002103289],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.1101586,0.3700026,0.1671793,0.2611936,0.06120689,0.000743041,0.0007801214,0.003306722,0.02542909],"genre_scores_gemma":[0.4192894,0.1816273,0.1241054,0.1745246,0.02156322,0.001212489,0.0006956405,0.0007162537,0.07626563],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.003677819,"threshold_uncertainty_score":0.01945037,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01170440385136526,"score_gpt":0.2330293076973255,"score_spread":0.2213249038459602,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}