{"id":"W2733097072","doi":"","title":"Response of breast cancer cell lines to aminoflavone (NSC 686288) is associated with histone H2AX phosphorylation and estrogen receptor expression","year":2006,"lang":"en","type":"article","venue":"Cancer Research","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Aryl hydrocarbon receptor; Estrogen receptor; Cancer research; DNA damage; Cell culture; Cell cycle; Cell growth; Molecular biology; Estrogen receptor alpha; Chemistry; Cancer; Breast cancer; Biology; Internal medicine; Medicine; DNA; Transcription factor; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001164697,0.000317871,0.0003197396,0.0002855759,0.0001493191,0.00018574,0.0001440379,0.0002619,0.001602235],"category_scores_gemma":[0.00009685285,0.0001623324,0.0002514024,0.0003427073,0.0001182978,0.0001083424,0.0001227116,0.0003726448,0.0004784992],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002297051,"about_ca_system_score_gemma":0.0001547138,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001999143,"about_ca_topic_score_gemma":0.003536508,"domain_scores_codex":[0.9997827,0.00003270677,0.00002510855,0.00002705478,0.00007916318,0.0000532646],"domain_scores_gemma":[0.999912,0.00002207338,0.00001752751,0.00001208258,0.00002025061,0.00001604744],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002632709,0.0001437213,0.001003603,0.00004011778,0.0000130278,0.00005110255,0.00003610454,0.0000723349,0.9967588,0.00003113635,0.0001376422,0.001449114],"study_design_scores_gemma":[0.00002846939,0.001557182,0.02317857,0.00000629208,0.0000253515,0.0002783209,0.00007873525,0.0006628545,0.9724845,0.0000183589,0.001675648,0.000005659587],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948522,0.001396187,0.0007332676,0.00009193773,0.00002378314,0.00003511137,0.001039292,0.00004939093,0.001778801],"genre_scores_gemma":[0.9887401,0.001615251,0.001608602,0.000116307,0.00001175254,0.0001145227,0.003537027,0.00001047027,0.004245967],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001999143,"threshold_uncertainty_score":0.005360007,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0123080474243176,"score_gpt":0.3186665609660291,"score_spread":0.3063585135417115,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}