{"id":"W2733401425","doi":"10.1039/c7nj01406f","title":"Acyclonucleosides bearing coplanar arylethynyltriazole nucleobases: synthesis, structural analysis, and biological evaluation","year":2017,"lang":"en","type":"article","venue":"New Journal of Chemistry","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Fundamental Research Funds for the Central Universities; National Natural Science Foundation of China; Chongqing University; Royal Society of Chemistry; Centre National de la Recherche Scientifique; Royal Society; University of Windsor","keywords":"Chemistry; Nucleobase; DNA; Bearing (navigation); Computational biology; Combinatorial chemistry; Stereochemistry; Biochemistry; Artificial intelligence","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001261989,0.0003337118,0.0002086695,0.0001786029,0.0001345993,0.0001802659,0.0001531782,0.0002496932,0.001075339],"category_scores_gemma":[0.0001823205,0.00008397874,0.0001201224,0.000212393,0.0001416589,0.0002066257,0.0001253584,0.0002871113,0.0002306621],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001921747,"about_ca_system_score_gemma":0.0001772369,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000535757,"about_ca_topic_score_gemma":0.001186018,"domain_scores_codex":[0.9999071,0.00001263857,0.00001016147,0.0000224471,0.00002568311,0.0000220058],"domain_scores_gemma":[0.9998906,0.00002157948,0.00003299726,0.00001464341,0.00002007232,0.00002015408],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004611001,0.00001136213,0.00007936511,0.00003473841,0.000003134377,0.00007408006,0.0000131191,0.00011553,0.9966738,0.000102493,0.00002093887,0.002825301],"study_design_scores_gemma":[0.000005714765,0.0002557349,0.0006459043,0.000002719219,0.000009576219,0.0001572809,0.000006310875,0.0002141137,0.9974864,0.00001647876,0.001196406,0.000003432704],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9870787,0.002556388,0.00667758,0.00004412046,0.00001689855,0.0000878999,0.0003355555,0.0001083612,0.003094401],"genre_scores_gemma":[0.9902998,0.001505522,0.006017379,0.00002321549,0.000006868936,0.00004981881,0.0004184494,0.00001835259,0.001660633],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001075339,"threshold_uncertainty_score":0.003597319,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03814959220609279,"score_gpt":0.3152975736619297,"score_spread":0.2771479814558369,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}