{"id":"W2734193803","doi":"10.1128/aac.00778-17","title":"Subinhibitory Concentrations of Trimethoprim and Sulfamethoxazole Prevent Biofilm Formation by Acinetobacter baumannii through Inhibition of Csu Pilus Expression","year":2017,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Biofilm; Pilus; Acinetobacter baumannii; Microbiology; Antibiotics; Virulence; Acinetobacter; Biology; Bacteria; Efflux; Pathogen; Chemistry; Biochemistry; Gene; Pseudomonas aeruginosa; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009421586,0.0002972488,0.0002793616,0.000140508,0.0001190299,0.0001662527,0.0002206066,0.0002275303,0.001149585],"category_scores_gemma":[0.0001612606,0.00008565714,0.0001488982,0.0001424699,0.0001457094,0.0001010586,0.0001532919,0.0003388966,0.0002329954],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000184712,"about_ca_system_score_gemma":0.0002454153,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001430585,"about_ca_topic_score_gemma":0.002124292,"domain_scores_codex":[0.9998512,0.00002901312,0.00001985723,0.00001749936,0.00004697855,0.00003532096],"domain_scores_gemma":[0.9998924,0.00002835363,0.00002303507,0.00001158535,0.0000176051,0.00002701856],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001506437,0.0000834227,0.0001824583,0.00003494031,0.000003092192,0.00001709303,0.00001163269,0.00003619374,0.9983574,0.0000162668,0.00005134174,0.001055535],"study_design_scores_gemma":[0.00002453734,0.001580217,0.008373652,0.00001048375,0.0000119319,0.0001060413,0.00005756537,0.0007719958,0.9877232,0.00002534487,0.001310126,0.000004907839],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973915,0.001055505,0.0003136667,0.0001038751,0.00002880175,0.00002316962,0.0001930116,0.00004030601,0.0008502663],"genre_scores_gemma":[0.9967889,0.0004448983,0.001195613,0.00005180951,0.00001344419,0.00003066812,0.0003564581,0.000007367948,0.001110862],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001430585,"threshold_uncertainty_score":0.003845751,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01334453692731101,"score_gpt":0.273159919657969,"score_spread":0.259815382730658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}