{"id":"W2734219605","doi":"10.1186/s13058-017-0867-9","title":"Ex vivo expanded natural killer cells from breast cancer patients and healthy donors are highly cytotoxic against breast cancer cell lines and patient-derived tumours","year":2017,"lang":"en","type":"article","venue":"Breast Cancer Research","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":79,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; McMaster University Medical Centre","funders":"Cure Brain Cancer Foundation; Canadian Cancer Society","keywords":"Ex vivo; Breast cancer; Cancer research; Cytotoxic T cell; Cancer; Immunosurveillance; Immunology; Medicine; In vivo; Cancer cell; Surgical oncology; Lymphokine-activated killer cell; Biology; Interleukin 21; T cell; In vitro; Immune system; Oncology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003474082,0.0002865285,0.0004779211,0.0001805552,0.0001081495,0.0003426505,0.0001525301,0.0003640286,0.005302999],"category_scores_gemma":[0.0005987521,0.0001194603,0.0002077004,0.0001489143,0.0001691656,0.0002319999,0.0004066649,0.0006203493,0.001096545],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001006877,"about_ca_system_score_gemma":0.0001329364,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001104042,"about_ca_topic_score_gemma":0.0001111501,"domain_scores_codex":[0.9994992,0.0001071504,0.00007072782,0.0001264331,0.0001243508,0.00007203256],"domain_scores_gemma":[0.9996781,0.0001154846,0.00004082955,0.00006564619,0.00005061447,0.00004927337],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002034924,0.0004394533,0.01134542,0.000241177,0.00006132983,0.00118279,0.0003292045,0.0002637496,0.9552779,0.0001192495,0.0006025708,0.02810229],"study_design_scores_gemma":[0.000458919,0.008219348,0.1494233,0.000109146,0.0002846631,0.025658,0.0006217739,0.001901387,0.7832367,0.0003509393,0.02967222,0.0000635605],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925678,0.002900022,0.001704981,0.0000907442,0.00006419239,0.00009304962,0.0004542323,0.00005235224,0.002072665],"genre_scores_gemma":[0.9921071,0.0007545803,0.001179479,0.0001731833,0.00004162786,0.0001512537,0.002565886,0.00002344696,0.003003482],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005302999,"threshold_uncertainty_score":0.01774031,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01949868368367795,"score_gpt":0.3013461220239645,"score_spread":0.2818474383402866,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}