{"id":"W2734446741","doi":"10.1038/s41467-017-00147-w","title":"Evasion of immunosurveillance by genomic alterations of PPARγ/RXRα in bladder cancer","year":2017,"lang":"en","type":"article","venue":"Nature Communications","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":145,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Eisai","keywords":"Cancer research; Immunosurveillance; Immune system; Peroxisome proliferator-activated receptor; Gene knockdown; Biology; Immunotherapy; Immunology; Receptor; Cell culture; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001743035,0.00014526,0.0001714661,0.0002271995,0.00009623419,0.0002355143,0.0001015092,0.000207071,0.0007231589],"category_scores_gemma":[0.00009664637,0.0000949896,0.000167572,0.0001428404,0.000206438,0.00009871367,0.0001358194,0.000311695,0.0001632519],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001798213,"about_ca_system_score_gemma":0.0001392834,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002026882,"about_ca_topic_score_gemma":0.0002818752,"domain_scores_codex":[0.9998889,0.00003420786,0.000007813709,0.00001753229,0.00002350357,0.00002804839],"domain_scores_gemma":[0.9999388,0.00000892439,0.00001963307,0.00001199928,0.000009209253,0.00001135324],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002134982,0.00003253918,0.001864612,0.00003467059,0.000009283629,0.0001274811,0.00001986898,0.0001880333,0.9936766,0.0001698067,0.00006090928,0.003602827],"study_design_scores_gemma":[0.00003856936,0.001206071,0.03343128,0.00001550418,0.00004359121,0.001993749,0.000132578,0.001689328,0.9563414,0.0003604719,0.004740189,0.000007424005],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995574,0.001782581,0.001566259,0.0001463467,0.00001875358,0.000007812378,0.00008687492,0.00003804144,0.0007793848],"genre_scores_gemma":[0.9982176,0.0006668387,0.0003940216,0.00003666941,0.000007091012,0.000006851922,0.00009058353,0.000005391893,0.0005748427],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007231589,"threshold_uncertainty_score":0.002419174,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01875627741126124,"score_gpt":0.3257973601877897,"score_spread":0.3070410827765285,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}