{"id":"W2734624925","doi":"10.1161/hyp.62.suppl_1.a352","title":"Abstract 352: A Common Hypofunctional Genetic Variant of GPER: Increased Blood Pressure in Female Carriers and Increased Expression in Female Hypertensive Patients","year":2013,"lang":"en","type":"article","venue":"Hypertension","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Robarts Clinical Trials","funders":"","keywords":"GPER; Blood pressure; Endocrinology; Internal medicine; Medicine; Allele; Estrogen receptor; Biology; Genetics; Breast cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001252219,0.0002421504,0.0003709157,0.0001335519,0.00006308208,0.00001536008,0.0001093921,0.0003817005,0.00002470687],"category_scores_gemma":[0.0001640563,0.0002020383,0.00007313493,0.000129839,0.00009540741,0.00001625244,0.0001215446,0.0002154513,0.000006123772],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009155677,"about_ca_system_score_gemma":0.00006406028,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001544205,"about_ca_topic_score_gemma":0.00004357482,"domain_scores_codex":[0.998507,0.0001467083,0.0003798565,0.0004638353,0.0002090567,0.0002935277],"domain_scores_gemma":[0.9991623,0.00006247842,0.0001342981,0.000318798,0.0001657062,0.0001564341],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002563211,0.0004506486,0.1718827,0.00005654051,0.00006100426,0.00005306446,0.00006200963,0.00008786209,0.8260934,0.000001086716,0.000273016,0.0007223595],"study_design_scores_gemma":[0.003676506,0.0004468166,0.7874124,0.0001812575,0.0001028315,0.00007599538,0.0001208209,0.0005347108,0.2070681,0.00001668511,0.0001115478,0.0002523759],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954968,0.003637575,0.000001966316,0.00002272297,0.00008762628,0.0005716627,0.00002132551,0.000009561853,0.0001507284],"genre_scores_gemma":[0.9988396,0.0002840697,0.0003759991,0.0001787378,0.00004363939,0.00004869009,0.0001797419,0.00003034171,0.00001919008],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6190253,"threshold_uncertainty_score":0.8238883,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006133939326581864,"score_gpt":0.1922822679055785,"score_spread":0.1861483285789966,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}