{"id":"W2734948582","doi":"10.1016/j.bbrc.2017.07.064","title":"Copper chaperone ATOX1 regulates pluripotency factor OCT4 in preimplantation mouse embryos","year":2017,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Sahlgrenska Akademin; Fondation Chalmers; Vetenskapsrådet; Knut och Alice Wallenbergs Stiftelse; Svenska Sällskapet för Medicinsk Forskning; Fondation pour la Recherche Médicale","keywords":"Inner cell mass; Biology; Embryo; Cell biology; Transcription factor; Embryonic stem cell; Transcription (linguistics); Chaperone (clinical); Cell; Gene silencing; Embryogenesis; Blastocyst; Molecular biology; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001733736,0.0002831055,0.0002597653,0.0004536499,0.000424123,0.0006106444,0.000398114,0.0003324486,0.001772383],"category_scores_gemma":[0.0001773142,0.0002858244,0.0002620649,0.0001729465,0.0003251378,0.0004354913,0.0004777065,0.0006530676,0.000409211],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008211237,"about_ca_system_score_gemma":0.0003624491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001737971,"about_ca_topic_score_gemma":0.003442114,"domain_scores_codex":[0.9997787,0.00001742352,0.00001236955,0.00006077499,0.00004836171,0.00008232891],"domain_scores_gemma":[0.9997359,0.00002532877,0.00007395227,0.00002327222,0.00004565205,0.0000958388],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001587646,0.00001037995,0.0003867712,0.00001589308,0.000003780501,0.00004881699,0.00001609861,0.00002540909,0.9983904,0.0001988441,0.0001064943,0.0006383107],"study_design_scores_gemma":[0.0000213814,0.000060618,0.01842898,0.000009382268,0.00002126831,0.00009667165,0.00008619928,0.0007515327,0.9785132,0.0001569821,0.001847055,0.000006761895],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929948,0.001345358,0.002642371,0.0002065198,0.00006473913,0.00001108911,0.0003793875,0.0001790849,0.002176633],"genre_scores_gemma":[0.9908378,0.0003611412,0.0007783981,0.00009291374,0.0000144009,0.00001616559,0.0004113351,0.0001166909,0.007371202],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001772383,"threshold_uncertainty_score":0.005957723,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07275950712669181,"score_gpt":0.3748372473559768,"score_spread":0.302077740229285,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}