{"id":"W2734981423","doi":"10.1371/journal.pgen.1006883","title":"Systematic identification and characterization of regulatory elements derived from human endogenous retroviruses","year":2017,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Chromosomal and Genetic Variations","field":"Agricultural and Biological Sciences","cited_by":192,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; Japan Society for the Promotion of Science","keywords":"Biology; DNA binding site; Transcription factor; Genetics; Long terminal repeat; Endogenous retrovirus; Computational biology; Regulatory sequence; GATA transcription factor; Gene; Genome; Promoter; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004166319,0.0002878645,0.0005765873,0.001218581,0.0002350616,0.0005877824,0.0003826071,0.0002834525,0.0007546983],"category_scores_gemma":[0.001015666,0.0002735393,0.0005462788,0.0009630137,0.0002324518,0.000271917,0.0003869363,0.0005191237,0.0005387112],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002689386,"about_ca_system_score_gemma":0.00041673,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000830608,"about_ca_topic_score_gemma":0.00172602,"domain_scores_codex":[0.9994965,0.00004507073,0.00004209503,0.0001897109,0.0001649122,0.00006184059],"domain_scores_gemma":[0.999402,0.0001858275,0.00015932,0.00008009783,0.0001033672,0.0000693804],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003088986,0.00004984311,0.02534219,0.0006724714,0.00009722726,0.0002766347,0.0001518191,0.001119521,0.9458869,0.0007088915,0.0006071937,0.02477852],"study_design_scores_gemma":[0.00008173579,0.0005143678,0.2696842,0.0003003041,0.0005503519,0.003453231,0.0004087441,0.02239628,0.6525695,0.001667554,0.04827986,0.00009388274],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9475559,0.008126616,0.02348966,0.00007895514,0.00004638445,0.0001266988,0.01824856,0.0004163091,0.001910951],"genre_scores_gemma":[0.8893723,0.004115318,0.04581274,0.0003664012,0.00005243364,0.0001828999,0.05833246,0.0002486113,0.001516782],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001218581,"threshold_uncertainty_score":0.002524674,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05073707396468481,"score_gpt":0.2313981089769613,"score_spread":0.1806610350122764,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}