{"id":"W2735051861","doi":"10.1111/acel.12646","title":"The emerging role of alternative splicing in senescence and aging","year":2017,"lang":"en","type":"review","venue":"Aging Cell","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":170,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Biology; Senescence; Alternative splicing; Computational biology; Cellular senescence; RNA splicing; Cell biology; Genetics; Gene; Phenotype; RNA; Exon","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006420476,0.0006899511,0.001024728,0.001589038,0.0003599514,0.00107829,0.0006564197,0.001432484,0.002658387],"category_scores_gemma":[0.00058296,0.0001995356,0.0003877405,0.001584247,0.0007350018,0.001627547,0.0009363993,0.001994496,0.001538173],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000512906,"about_ca_system_score_gemma":0.001159315,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005355799,"about_ca_topic_score_gemma":0.0007718262,"domain_scores_codex":[0.9998349,0.00003088813,0.00002928992,0.00003214836,0.00005403738,0.00001875009],"domain_scores_gemma":[0.999681,0.0001413204,0.00004573198,0.00001207552,0.00007885984,0.00004099486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008155547,0.0000467484,0.0003336658,0.01329007,0.00008679026,0.0005073044,0.0001437711,0.0003268026,0.00535947,0.01024437,0.02234381,0.9472356],"study_design_scores_gemma":[0.000007949933,0.00008310481,0.0009021931,0.001838011,0.00007720503,0.002374447,0.00009081199,0.00007764162,0.001154498,0.005314124,0.9880563,0.00002356128],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001339038,0.9982613,0.0002347499,0.0003991194,0.0002872022,0.000002218563,0.0000128021,0.00001015212,0.0006585624],"genre_scores_gemma":[0.0008095988,0.9980308,0.0002188554,0.0002246989,0.0003146632,0.000004117573,0.0000230188,0.000001736269,0.0003723954],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002658387,"threshold_uncertainty_score":0.008893251,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0282932128504752,"score_gpt":0.3549779553521518,"score_spread":0.3266847425016766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}