{"id":"W2735227029","doi":"10.3390/genes8070178","title":"EYS Mutations Causing Autosomal Recessive Retinitis Pigmentosa: Changes of Retinal Structure and Function with Disease Progression","year":2017,"lang":"en","type":"article","venue":"Genes","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Institutes of Health; National Eye Institute; Chatlos Foundation; Macula Vision Research Foundation","keywords":"Retinitis pigmentosa; Ciliopathies; Ophthalmology; Retina; Retinal; Ciliopathy; Retinal degeneration; Biology; Medicine; Genetics; Gene; Neuroscience","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003553504,0.0000934889,0.00007395556,0.00002345578,0.0002684965,0.00004209553,0.00005510889,0.00005101608,0.00001125371],"category_scores_gemma":[0.00003933764,0.00007320787,0.00001460246,0.00002050657,0.0001490372,0.000006003385,0.00006343552,0.00002833221,2.13841e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000027436,"about_ca_system_score_gemma":0.00005323312,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009457532,"about_ca_topic_score_gemma":0.00008045316,"domain_scores_codex":[0.9995007,0.00002087558,0.00007497472,0.0001967798,0.0001002808,0.0001064018],"domain_scores_gemma":[0.9995431,0.000003125031,0.0001527592,0.000170228,0.00007496578,0.00005580524],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008511953,0.00002825365,0.5322672,0.0001274996,0.00005913515,0.000014885,0.0001607086,0.00001259596,0.4005736,0.00006230424,0.0001190698,0.0657236],"study_design_scores_gemma":[0.0007079426,0.0004389635,0.7591988,0.0001413268,0.00007529215,0.00001553514,0.0002146881,0.00003019994,0.2360838,0.0002926008,0.002588652,0.0002120889],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976774,0.001096266,0.0002205335,0.0004743312,0.0000738972,0.000131045,0.00002078495,0.000005921313,0.0002997562],"genre_scores_gemma":[0.9981679,0.0002675217,0.001103244,0.00002205657,0.00008526278,0.00001306495,0.000180978,0.000009479649,0.0001504875],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2269317,"threshold_uncertainty_score":0.298533,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01029076535990045,"score_gpt":0.2613781689749365,"score_spread":0.2510874036150361,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}