{"id":"W2735227029","doi":"10.3390/genes8070178","title":"EYS Mutations Causing Autosomal Recessive Retinitis Pigmentosa: Changes of Retinal Structure and Function with Disease Progression","year":2017,"lang":"en","type":"article","venue":"Genes","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Institutes of Health; National Eye Institute; Chatlos Foundation; Macula Vision Research Foundation","keywords":"Retinitis pigmentosa; Ciliopathies; Ophthalmology; Retina; Retinal; Ciliopathy; Retinal degeneration; Biology; Medicine; Genetics; Gene; Neuroscience","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002513394,0.0004187609,0.0003375352,0.0005722144,0.0003507588,0.0002974563,0.0001321269,0.0002735563,0.0008051558],"category_scores_gemma":[0.0006368376,0.0001626795,0.0002417449,0.0003185403,0.0003034026,0.0002351152,0.0003442734,0.0002555095,0.000262821],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002200631,"about_ca_system_score_gemma":0.0001671852,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001594033,"about_ca_topic_score_gemma":0.001431903,"domain_scores_codex":[0.9998541,0.00002015661,0.00002417303,0.00003834431,0.00003564436,0.00002760026],"domain_scores_gemma":[0.9996965,0.00004700412,0.0001175828,0.00002253143,0.00004325765,0.00007309471],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001817503,0.0002057998,0.7035436,0.00009370158,0.00007486753,0.03047939,0.002370134,0.0007821079,0.2296527,0.0003561719,0.0004171027,0.03020689],"study_design_scores_gemma":[0.00004643729,0.0007115341,0.9330851,0.0000191715,0.0000469867,0.05133044,0.0003366114,0.0007948047,0.01236179,0.0001647558,0.001080935,0.00002141215],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.999429,0.0001114683,0.0001341002,0.000008266758,0.000001086248,0.000006370577,0.00006272346,0.000008324345,0.0002386164],"genre_scores_gemma":[0.9992631,0.00008922915,0.0002354853,0.00001002466,0.000003033625,0.000005185816,0.00009131799,0.000003921289,0.0002987376],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001594033,"threshold_uncertainty_score":0.003169477,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01029076535990045,"score_gpt":0.2613781689749365,"score_spread":0.2510874036150361,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}