{"id":"W2735375447","doi":"10.1016/j.lungcan.2017.07.012","title":"Lack of response to nivolumab in a patient with EGFR -mutant non-small cell lung cancer adenocarcinoma sub-type transformed to small cell lung cancer","year":2017,"lang":"en","type":"article","venue":"Lung Cancer","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Niilo Helanderin Säätiö; Institute of Cancer Research","keywords":"Nivolumab; Medicine; Lung cancer; Adenocarcinoma; Oncology; Cancer research; Mutant; Cell; Internal medicine; Cancer; Immunotherapy; Gene; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000169759,0.0004253949,0.0006008589,0.0005359917,0.0007922832,0.0005923415,0.0005442973,0.001728573,0.001199172],"category_scores_gemma":[0.001148613,0.0002056577,0.0007805311,0.0003331673,0.0004168387,0.0003541957,0.0002467962,0.001299446,0.0004120859],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008001057,"about_ca_system_score_gemma":0.000427279,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003869781,"about_ca_topic_score_gemma":0.004900829,"domain_scores_codex":[0.9998003,0.00002158083,0.00003196135,0.00005220959,0.00003238825,0.00006160418],"domain_scores_gemma":[0.9994561,0.0001772148,0.00005929277,0.00003086041,0.00006577861,0.0002107557],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.001247199,0.0002100729,0.1128041,0.00007932541,0.00007402591,0.8628219,0.0002918126,0.0003431745,0.01144327,0.0002222779,0.001009645,0.009453253],"study_design_scores_gemma":[0.00008999615,0.00184118,0.1610249,0.0000398647,0.0002008335,0.8256606,0.0005646451,0.002033961,0.004979356,0.0003157633,0.003208957,0.00004000118],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894307,0.001347626,0.000390705,0.002296785,0.0001527726,0.00004603601,0.000239519,0.00004683166,0.006049125],"genre_scores_gemma":[0.9983627,0.0002241751,0.0001294305,0.0005670234,0.00006238507,0.000003696974,0.0001008308,0.000008221486,0.0005415333],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003869781,"threshold_uncertainty_score":0.007694483,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0179483754624601,"score_gpt":0.3245573099012019,"score_spread":0.3066089344387418,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}