{"id":"W2735547909","doi":"10.1097/j.pain.0000000000001016","title":"Distinct behavioral responses evoked by selective optogenetic stimulation of the major TRPV1+ and MrgD+ subsets of C-fibers","year":2017,"lang":"en","type":"article","venue":"Pain","topic":"Neurobiology and Insect Physiology Research","field":"Neuroscience","cited_by":91,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"McGill University","keywords":"Optogenetics; Nociceptor; TRPV1; Neuroscience; Nociception; Somatosensory system; Stimulation; Chemistry; Sensory system; Transient receptor potential channel; Noxious stimulus; Electrophysiology; Psychology; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006771557,0.00007534954,0.0001317496,0.0000319099,0.000304817,0.000009859755,0.0003029226,0.00005930706,0.0000172946],"category_scores_gemma":[0.00225576,0.00005332697,0.00003644443,0.00006347508,0.0008832834,0.00005762212,0.0001115778,0.0001265726,0.000001663207],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007899604,"about_ca_system_score_gemma":0.00003754848,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005771594,"about_ca_topic_score_gemma":0.00001296858,"domain_scores_codex":[0.9978396,0.001567356,0.0001303942,0.0002172846,0.00009433931,0.0001510395],"domain_scores_gemma":[0.9984307,0.001032595,0.000151282,0.0003239646,0.00003405204,0.00002738194],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002941604,0.00005581725,0.1092705,0.000008505061,0.000002654594,8.224645e-7,0.00009660245,0.000001341974,0.8896542,0.00002318454,0.0001548243,0.00043742],"study_design_scores_gemma":[0.0002015472,0.0001887441,0.4290184,0.000006859728,0.000007034389,0.000001470311,0.000004922189,0.0001813734,0.5701166,0.0002282024,0.000009992824,0.00003490024],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99937,0.00002473077,0.00001421188,0.0001262128,0.00005003303,0.0002183059,0.0000532327,0.000006377617,0.0001369221],"genre_scores_gemma":[0.999632,0.00000616457,0.00001082081,0.00004218429,0.00000724812,0.00001037178,0.000001361469,0.000006336653,0.0002835196],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3197479,"threshold_uncertainty_score":0.3254495,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04430521315701651,"score_gpt":0.3435570550372747,"score_spread":0.2992518418802582,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}