{"id":"W2735668298","doi":"10.1002/9781119384434.ch11","title":"Analytical Tools for Biologics Molecular Assessment","year":2017,"lang":"en","type":"other","venue":"","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Microsemi (Canada)","funders":"","keywords":"Biopharmaceutical; Computational biology; Workflow; Drug discovery; Biochemical engineering; Biotechnology; Chemistry; Nanotechnology; Pharmacology; Computer science; Bioinformatics; Medicine; Biology; Engineering; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004426182,0.001741997,0.001087165,0.007087295,0.0009575548,0.003215399,0.001849493,0.001947745,0.0169278],"category_scores_gemma":[0.006253794,0.0009026694,0.001003696,0.003010985,0.0018307,0.003561277,0.00312675,0.003894649,0.01723375],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001269561,"about_ca_system_score_gemma":0.001679853,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001100149,"about_ca_topic_score_gemma":0.001263265,"domain_scores_codex":[0.9951683,0.0008826027,0.0002971556,0.0006065322,0.002839596,0.0002057454],"domain_scores_gemma":[0.996821,0.0008445306,0.0003962027,0.0005077906,0.001267574,0.0001629145],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002993422,0.0004306878,0.003172897,0.002530622,0.0001697197,0.0008645016,0.0004908591,0.001793296,0.3673938,0.0809039,0.04823988,0.4937105],"study_design_scores_gemma":[0.0000336326,0.0002270254,0.002115309,0.0005960719,0.0000956008,0.002376975,0.0002985282,0.00723468,0.2603521,0.02944273,0.6971198,0.0001075908],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"other","genre_scores_codex":[0.0134051,0.07171249,0.7391782,0.004421839,0.002009031,0.0009049174,0.003305881,0.008787823,0.1562747],"genre_scores_gemma":[0.1298297,0.05681145,0.7015777,0.004287398,0.00132295,0.001552692,0.004160739,0.002218187,0.09823917],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.0169278,"threshold_uncertainty_score":0.05662918,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1137628313808604,"score_gpt":0.4642110844269082,"score_spread":0.3504482530460478,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}