{"id":"W2735819532","doi":"10.4049/immunohorizons.1700022","title":"Transfection of FcγRIIIa (CD16) Alone Can Be Sufficient To Enable Human αβTCR T Lymphocytes To Mediate Antibody-Dependent Cellular Cytotoxicity","year":2017,"lang":"en","type":"article","venue":"ImmunoHorizons","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotel Dieu Hospital","funders":"Institut National de la Santé et de la Recherche Médicale","keywords":"Antibody-dependent cell-mediated cytotoxicity; CD16; Transfection; Fc receptor; Jurkat cells; Cell biology; Molecular biology; Biology; Immunology; CD3; Chemistry; Antibody; Immune system; Monoclonal antibody; T cell; Cell culture; CD8","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001107428,0.0003500807,0.0007587718,0.0004368581,0.0007549279,0.0001287704,0.0006796853,0.0001914686,0.001381267],"category_scores_gemma":[0.0002370149,0.00033832,0.0002767933,0.0003265166,0.0002240738,0.0001158293,0.0002555009,0.000365921,0.0001060202],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006635303,"about_ca_system_score_gemma":0.0003486644,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01091107,"about_ca_topic_score_gemma":0.001585223,"domain_scores_codex":[0.9966771,0.0001248477,0.0005987851,0.0006448597,0.0010783,0.0008761121],"domain_scores_gemma":[0.9970801,0.0000808258,0.000153989,0.001800591,0.0003619237,0.0005225037],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006446447,0.0005709659,0.003723931,0.000100309,0.0002080985,0.00008763636,0.00185858,0.00003630505,0.9909444,0.000191951,0.0003507191,0.001282395],"study_design_scores_gemma":[0.002893638,0.00261637,0.01635739,0.0001721177,0.0001139598,0.00002825503,0.0003148828,0.000039291,0.9721004,0.00004684453,0.004995273,0.0003215563],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901312,0.0002104381,0.0005087617,0.001573006,0.0007607612,0.001808968,0.0001235402,0.0001026274,0.004780697],"genre_scores_gemma":[0.9920502,0.0001147914,0.0001278732,0.0001743825,0.0003563612,0.0001086416,0.00007729964,0.0000847886,0.006905672],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01884405,"threshold_uncertainty_score":0.9999069,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0320016045442368,"score_gpt":0.34345838496718,"score_spread":0.3114567804229432,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}