{"id":"W2735819532","doi":"10.4049/immunohorizons.1700022","title":"Transfection of FcγRIIIa (CD16) Alone Can Be Sufficient To Enable Human αβTCR T Lymphocytes To Mediate Antibody-Dependent Cellular Cytotoxicity","year":2017,"lang":"en","type":"article","venue":"ImmunoHorizons","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotel Dieu Hospital","funders":"Institut National de la Santé et de la Recherche Médicale","keywords":"Antibody-dependent cell-mediated cytotoxicity; CD16; Transfection; Fc receptor; Jurkat cells; Cell biology; Molecular biology; Biology; Immunology; CD3; Chemistry; Antibody; Immune system; Monoclonal antibody; T cell; Cell culture; CD8","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004182105,0.0003948806,0.0004020464,0.0001512398,0.000117008,0.0005938126,0.0001424309,0.0003448944,0.002551024],"category_scores_gemma":[0.0002550434,0.0001403923,0.000284731,0.0001892836,0.0002075488,0.0001727718,0.0002708913,0.0006820058,0.001178503],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002487613,"about_ca_system_score_gemma":0.000327138,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004229927,"about_ca_topic_score_gemma":0.0003391155,"domain_scores_codex":[0.9995286,0.00009292368,0.00007148003,0.00009537076,0.000113609,0.00009801603],"domain_scores_gemma":[0.9998052,0.00005107766,0.00003183174,0.00006324216,0.00002769615,0.00002109875],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008202939,0.00004514675,0.0001532312,0.00004196537,0.000005911424,0.00004202893,0.0000369122,0.00009629074,0.9981269,0.000121723,0.00003478428,0.001213112],"study_design_scores_gemma":[0.00002802204,0.0002678799,0.0006009281,0.000007607412,0.00002062906,0.0002203814,0.00001798412,0.000645196,0.9920269,0.00003152171,0.006129587,0.000003344417],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98104,0.0008784726,0.01400941,0.000081334,0.0001050871,0.0001835722,0.0004698879,0.0001584344,0.003073759],"genre_scores_gemma":[0.9852684,0.0007286321,0.008129568,0.00005716223,0.00002302936,0.0001556812,0.001169161,0.00005923435,0.004409118],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002551024,"threshold_uncertainty_score":0.008534014,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0320016045442368,"score_gpt":0.34345838496718,"score_spread":0.3114567804229432,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}