{"id":"W2736010401","doi":"10.1002/9781119413073.ch9","title":"Nonspecific Binding in LC–MS Bioanalysis","year":2017,"lang":"en","type":"other","venue":"","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Nucro Technics","funders":"","keywords":"Bioanalysis; Molecular biomarkers; Biomarker; Chemistry; Nanotechnology; Computational biology; Chromatography; Biology; Materials science; Biochemistry; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01014322,0.002001695,0.001418199,0.002103323,0.001854423,0.004647156,0.002182519,0.004231658,0.007086956],"category_scores_gemma":[0.008585145,0.00152811,0.0009227119,0.001616885,0.004104733,0.00366819,0.004011364,0.005261838,0.01160077],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00199401,"about_ca_system_score_gemma":0.001940109,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001290821,"about_ca_topic_score_gemma":0.002301523,"domain_scores_codex":[0.9822977,0.004048074,0.0007204511,0.002519618,0.009835812,0.000578393],"domain_scores_gemma":[0.9955382,0.001969823,0.0004884677,0.0005712383,0.001263946,0.000168348],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003154437,0.0002393667,0.003171462,0.005326267,0.0003253493,0.001653143,0.001107248,0.001977123,0.6141475,0.05018468,0.05379635,0.267756],"study_design_scores_gemma":[0.00003574851,0.000339759,0.001878647,0.0008734021,0.0001237147,0.004964599,0.0003840685,0.00542449,0.5075271,0.02194084,0.4563394,0.0001683718],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.03322987,0.1910861,0.6380305,0.01140019,0.008752028,0.00141358,0.001208284,0.005613827,0.1092656],"genre_scores_gemma":[0.2030361,0.1917032,0.4443617,0.01720534,0.003808177,0.002001224,0.003169414,0.002978879,0.1317359],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.01014322,"threshold_uncertainty_score":0.05364311,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03313426440078781,"score_gpt":0.3107584605283986,"score_spread":0.2776241961276108,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}