{"id":"W2736041600","doi":"10.1111/nmo.13148","title":"Targeting fatty acid amide hydrolase and transient receptor potential vanilloid‐1 simultaneously to modulate colonic motility and visceral sensation in the mouse: A pharmacological intervention with N‐arachidonoyl‐serotonin (<scp>AA</scp>‐5‐<scp>HT</scp>)","year":2017,"lang":"en","type":"article","venue":"Neurogastroenterology & Motility","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Deutsche Forschungsgemeinschaft","keywords":"Fatty acid amide hydrolase; Chemistry; TRPV; Transient receptor potential channel; Endocannabinoid system; Pharmacology; Anandamide; TRPV1; Endocrinology; Internal medicine; Antagonist; Biochemistry; Receptor; Cannabinoid receptor; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001523611,0.0004591154,0.0006721131,0.0001691369,0.000569454,0.0001998203,0.0003925159,0.0002251246,0.00001689887],"category_scores_gemma":[0.001102178,0.000345878,0.0001793467,0.0001073445,0.0007362891,0.0002041748,0.0003022811,0.001217391,0.000005171147],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001519585,"about_ca_system_score_gemma":0.00004937586,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003328031,"about_ca_topic_score_gemma":0.0005989263,"domain_scores_codex":[0.9955258,0.001053883,0.0006636471,0.001185741,0.0005649432,0.001005921],"domain_scores_gemma":[0.9982563,0.000114082,0.000298876,0.0006520923,0.0002205815,0.000458096],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001166453,0.001921611,0.6510503,0.0002779082,0.0001895592,0.000737349,0.002478809,0.002405884,0.3356496,0.000002269617,0.002015823,0.002104481],"study_design_scores_gemma":[0.005731772,0.004677532,0.9533194,0.00003429671,0.0001495335,0.0003572586,0.0004074247,0.02733958,0.007387464,0.00001024302,0.0005553209,0.00003016597],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917307,0.00006662795,0.0006064213,0.004672858,0.0001572571,0.00254493,0.0001317928,0.00006981625,0.00001953339],"genre_scores_gemma":[0.9979649,0.0000478046,0.0002294025,0.001145799,0.0001223715,0.0002084474,0.0000792841,0.0000395031,0.0001624701],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3282622,"threshold_uncertainty_score":0.9998993,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0113841953250925,"score_gpt":0.2800021739590414,"score_spread":0.2686179786339489,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}