{"id":"W2736205326","doi":"10.1016/j.neuroscience.2017.07.006","title":"Length of axons expressing the serotonin transporter in orbitofrontal cortex is lower with age in depression","year":2017,"lang":"en","type":"article","venue":"Neuroscience","topic":"Neurotransmitter Receptor Influence on Behavior","field":"Neuroscience","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Hospital","funders":"National Institute of General Medical Sciences; National Institute of Mental Health; Canadian Institutes of Health Research","keywords":"Serotonin transporter; Orbitofrontal cortex; Serotonin Plasma Membrane Transport Proteins; Dorsal raphe nucleus; Major depressive disorder; Axon; Psychology; Antidepressant; Serotonin; Neuroscience; Prefrontal cortex; 5,7-Dihydroxytryptamine; Endocrinology; Internal medicine; Biology; Serotonergic; Medicine; Receptor; Hippocampus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002256924,0.0002555639,0.0002748083,0.0001532314,0.0003992439,0.0002216678,0.001855619,0.00006805988,0.00004289453],"category_scores_gemma":[0.0001272024,0.000172875,0.00006860268,0.0003462127,0.001522746,0.001112275,0.0001181723,0.0005241802,0.000007344328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002910287,"about_ca_system_score_gemma":0.00007780834,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001693727,"about_ca_topic_score_gemma":0.0002872047,"domain_scores_codex":[0.9972356,0.0001301083,0.000407584,0.0009297944,0.0007471665,0.0005497629],"domain_scores_gemma":[0.9983481,0.00008523244,0.0002775904,0.001171789,0.00001895948,0.00009835327],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00006842214,0.0001473926,0.2536636,0.00000773844,9.925474e-8,0.0004411957,0.0007100558,0.00003801411,0.7436537,0.00001167279,0.000008678556,0.001249478],"study_design_scores_gemma":[0.0005129616,0.00009186797,0.5729337,0.0001202323,0.000003294107,0.00003802308,0.0000207273,0.0001762498,0.4256491,0.00001171341,0.0003015479,0.000140566],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976869,0.000006885962,0.00006251631,0.0003138795,0.0004098187,0.0006900273,0.0000164318,0.00003050591,0.0007830244],"genre_scores_gemma":[0.998491,0.00001752783,0.00007405499,0.001153486,0.00001327359,0.00008024128,1.528722e-7,0.00002822263,0.0001420575],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3192701,"threshold_uncertainty_score":0.7049639,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04727836108273257,"score_gpt":0.3051136450112118,"score_spread":0.2578352839284792,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}