{"id":"W2736830325","doi":"10.1038/nchem.2814","title":"The versatility of boron in biological target engagement","year":2017,"lang":"en","type":"review","venue":"Nature Chemistry","topic":"Organoboron and organosilicon chemistry","field":"Chemistry","cited_by":323,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Chemistry; Electrophile; Boron; Heteroatom; Covalent bond; Nucleophile; Combinatorial chemistry; Small molecule; Molecule; Nanotechnology; Organic chemistry; Biochemistry; Materials science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003650943,0.0006469113,0.0005746514,0.0007421397,0.0001904406,0.0008492177,0.0004896856,0.0006537847,0.002856141],"category_scores_gemma":[0.0003055726,0.0002367984,0.000270334,0.0008164354,0.0004786927,0.001117265,0.0007388727,0.001250328,0.001128938],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005129082,"about_ca_system_score_gemma":0.0005537566,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005124159,"about_ca_topic_score_gemma":0.001223376,"domain_scores_codex":[0.9998937,0.00001615306,0.000007859559,0.00002346346,0.00003673505,0.00002215877],"domain_scores_gemma":[0.9999337,0.00003196522,0.000009377963,0.000004109219,0.0000129589,0.000007808138],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002098334,0.0000752595,0.0002132691,0.01090232,0.00009674429,0.0004491996,0.0001125046,0.00148554,0.04818719,0.0434427,0.02496617,0.8698593],"study_design_scores_gemma":[0.00002484215,0.0001574344,0.0002320717,0.000549398,0.00004355353,0.0006621626,0.00003714344,0.0002986107,0.01959479,0.005800493,0.9725771,0.00002234415],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002843868,0.9750292,0.003480391,0.0008314535,0.0007669387,0.0000168207,0.0001245435,0.00004469827,0.01686206],"genre_scores_gemma":[0.02483582,0.9674041,0.001453023,0.0005318059,0.0002674649,0.00002595091,0.000111238,0.00001079509,0.00535973],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002856141,"threshold_uncertainty_score":0.009554744,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06055435737116516,"score_gpt":0.3582294397454131,"score_spread":0.2976750823742479,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}