{"id":"W2737589253","doi":"10.1016/j.euroneuro.2017.07.002","title":"Pattern of gene expression in different stages of schizophrenia: Down-regulation of NPTX2 gene revealed by a meta-analysis of microarray datasets","year":2017,"lang":"en","type":"review","venue":"European Neuropsychopharmacology","topic":"Biomarkers in Disease Mechanisms","field":"Immunology and Microbiology","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health; Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"Microarray; Microarray analysis techniques; Gene expression profiling; Biology; Gene expression; Gene chip analysis; Computational biology; Meta-analysis; Schizophrenia (object-oriented programming); Gene; Bioinformatics; Genetics; Medicine; Pathology; Psychiatry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009857235,0.0007994876,0.006456207,0.001362814,0.00005344222,0.000006419966,0.001785492,0.0004286146,0.001207685],"category_scores_gemma":[0.0001006928,0.0006117065,0.002264588,0.0005496977,0.0006532336,0.00006895334,0.000535753,0.0005887016,0.00001715497],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000315229,"about_ca_system_score_gemma":0.00007761162,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002431548,"about_ca_topic_score_gemma":0.000004119569,"domain_scores_codex":[0.9886065,0.006846782,0.002886254,0.001075158,0.0001595261,0.0004258509],"domain_scores_gemma":[0.9920881,0.0004613372,0.005279938,0.001952286,0.0001524245,0.00006590153],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.0005411344,0.0008000373,0.00004581838,0.003133968,0.04631024,0.00002804332,0.00005047121,0.000005320772,0.9082931,9.267393e-7,0.00621763,0.03457332],"study_design_scores_gemma":[0.008455322,0.0008778575,0.008199373,0.001498899,0.487562,0.0000591419,0.00001345754,0.000004402507,0.3369488,0.000007561628,0.1550012,0.001371973],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01643524,0.9619089,0.0001862174,0.00001656605,0.0008309114,0.001191574,0.01933882,0.00002863422,0.00006318492],"genre_scores_gemma":[0.07267292,0.9181204,0.0002692713,0.00005357307,0.00004569556,0.00007493956,0.008308789,0.0002074178,0.0002470058],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.5713443,"threshold_uncertainty_score":0.9997054,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07000971690193966,"score_gpt":0.347245449612622,"score_spread":0.2772357327106824,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}